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The products of thermodegradation of fluorocarbon polymers (found in electrical insulation) will be toxic to space habitat crews, and the monitoring and detection of such contaminants are important to space environmental health. Experiments are therefore being performed on the thermodegradation of a liquid perfluoroalkane mixture (consisting of perfluorohexanes, C6F14, and −5% perfluoropentane, C5F12), similar in structure to polytetrafluoroethylene (PTFE - Teflon), in atmospheres of varying oxygen concentration. PTFE is a common material used on space vehicles for insulation of wires. When PTFE is thermally degraded, such as from the overheating of a wire and subsequent smoldering of the insulation, it may produce toxic compounds ranging from carbonyl fluoride and hydrogen fluoride through perfluorinated aromatic compounds to ultrafine particles.

It is well known that selection of the pressure/oxygen ratio for a human space habitat is a critical decision for the well-being and mission performance of astronauts. It has also been noted how this ratio affects the requirement for pre- and post-breathing and the type and flexibility of EVA/EHA astronaut suits. However, little attention has been paid to how these issues interact with various mission design strategies. Using the first manned mission to Mars as a baseline mission, we have separated the mission into its component parts as it relates to habitat type (i.e., the Earth-Mars interplanetary vehicle, the ascent/descent vehicle, the base, human rover vehicles, etc.) and have determined the oxygen resupply requirements for each part as they reflect a mission design strategy. These component parts form a matrix where duration of stay, loss of oxygen due to leakage and usage, and oxygen resupply needs are calculated.

Aeroponics is the process of growing plants in an air/mist environment without the use of soil or an aggregate media. Aeroponics has contributed to advances in several areas of study including root morphology, nutrient uptake, drought and flood stress, and responses to variations in oxygen and/or carbon dioxide root zone concentrations. The adaptability of the aeroponic process that has benefited researchers makes its application to spaceflight plant growth systems appealing. Greater control of growth parameters permits a greater range of crop performance throttling and the elimination of aggregates or common growth substrates lowers system mass, lessens disease propagation between plants, and can decrease the required crew time for both planting and harvesting.