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This paper presents a novel approach to determining the joint motion coupling relationship for the human shoulder complex. The human shoulder complex is the most sophisticated part in terms of degrees of freedom and motion. In the literature, different human shoulder biomechanical models have been developed for various purposes. Also, researchers have realized that there are constant movement relationships among the shoulder bones: the clavicle, scapula, and humerus. This is due to muscles and tendons that are involved in skeletal motions. These relationships, which are also called shoulder rhythm, entail joint motion coupling and joint limit coupling. However, the scope of this work is to determine the joint motion coupling relationship. This relationship is available in the literature, but it is an Euler-angle-based relationship. In the virtual human modeling environment, we cannot directly use this Euler-angle-based relationship.