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After several decades of human spaceflight, the community of space-faring nations has accumulated a diverse and sometimes harrowing history of toxicological events that have plagued human space endeavors almost from the very beginning. Some lessons have been learned in ground-based test beds and others were discovered the hard way - when human lives were at stake in space. From such lessons one can build a risk-management framework for toxicological events to minimize the probability of a harmful exposure, while recognizing that we cannot predict all possible events. Space toxicologists have learned that relatively harmless compounds can be converted by air revitalization systems into compounds that cause serious harm to the crew.

A tire may be one of the most critical and complex components in vehicle dynamics and road loads analyses because it serves as the only interface between the road surface and the vehicle. Extensive research and development activities about vehicle dynamics and tire models have been published in the past decades, but it is still not clear about the applications and parameter identification associated with all of these tire models. In this literature review study, various published tire models used for vehicle dynamics and road loads analyses are compared in terms of their modeling approaches, applications and parameters identification process and methodologies. It is hoped that the summary of this literature review work can help clarify and guide the future research and development direction about tire modeling.

A system performance study on a portable life support system being developed for use in the Weightless Environment Training Facility (WETF) and the Neutral Buoyancy Laboratory (NBL) has been completed. The Neutral Buoyancy Portable Life Support System (NBPLSS) will provide life support to suited astronauts training for extravehicular activity (EVA) under water without the use of umbilicals. The basic configuration is characterized by the use of medium pressure (200 - 300 psi) cryogen (liquid nitrogen/oxygen mixture) which provides cooling within the Extravehicular Mobility Unit (EMU), the momentum which enables flow in the vent loop, and oxygen for breathing. NBPLSS performance was analyzed by using a modified Metabolic Man program to compare competing configurations. Maximum sustainable steady state metabolic rates and transient performance based on a typical WETF metabolic rate profile were determined and compared.

The NASA-wide CEV Smart Buyer Team (SBT) was assembled in January 2006 and was tasked with the development of a NASA in-house design for the CEV Crew Module (CM), Service Module (SM), and Launch Abort System (LAS). This effort drew upon over 250 engineers from all of the 10 NASA Centers. In 6 weeks, this in-house design was developed. The Thermal Systems Team was responsible for the definition of the active and passive design architecture. The SBT effort for Thermal Systems can be best characterized as a design architecting activity. Proof-of-concepts were assessed through system-level trade studies and analyses using simplified modeling. This nimble design approach permitted definition of a point design and assessing its design robustness in a timely fashion. This paper will describe the architecting process and present trade studies and proposed thermal designs

An EVA simulation with a medical contingency scenario was conducted in 2006 with the NASA Haughton-Mars and EVA Physiology System and Performance Projects, to develop medical contingency management and evacuation techniques for planetary surface exploration. A rescue/evacuation system to allow two rescuer astronauts to evacuate one incapacitated astronaut was evaluated. The rescue system was utilized effectively to extract an injured astronaut up a slope of15-25° and into a surface mobility rover for transport to a simulated habitat for advanced medical care. Further research is recommended to evaluate the effects of reduced gravity and to develop synergies with other surface systems for carrying out the contingency procedures.

Carbon dioxide (CO2) removal technology development for portable life support systems (PLSS) has traditionally concentrated in the areas of solid and liquid chemical sorbents and semi-permeable membranes. Most of these systems are too heavy in gravity environments, require prohibitive amounts of consumables for operation on long term planetary missions, or are inoperable on the surface of Mars due to the presence of a CO2 atmosphere. This paper describes the effort performed to mature an innovative CO2 removal technology that meets NASA's planetary mission needs while adhering to the important guiding principles of simplicity, reliability, and operability. A breadboard cryogenic carbon dioxide scrubber for an ejector-based cryogenic PLSS was developed, designed, and tested. The scrubber freezes CO2 and other trace contaminants out of expired ventilation loop gas using cooling available from a liquid oxygen (LOX) based PLSS.

Providing water necessary to maintain life support has been accomplished in spacecraft vehicles for over forty years. This paper will investigate how previous U.S. space vehicles provided potable water. The water source for the spacecraft, biocide used to preserve the water on-orbit, water stowage methodology, materials, pumping mechanisms, on-orbit water requirements, and water temperature requirements will be discussed. Where available, the hardware used to provide the water and the general function of that hardware will also be detailed. The Crew Exploration Vehicle (CEV or Orion) water systems will be generically discussed to provide a glimpse of how similar they are to water systems in previous vehicles. Conclusions, questions, and recommendations on strategies that could be applied to CEV based on previous spacecraft water system lessons learned will be made.

Development of new air revitalization system (ARS) technology can initially be performed in a subscale laboratory environment, but in order to advance the maturity level, the technology must be tested in an end-to-end integrated environment. The Air Revitalization Technology Evaluation Facility (ARTEF) at the NASA Johnson Space Center (JSC) serves as a ground test bed for evaluating emerging ARS technologies in an environment representative of spacecraft atmospheres. At the center of the ARTEF is a hypobaric chamber which serves as a sealed atmospheric chamber for closed loop testing. A Human Metabolic Simulator (HMS) was custom-built to simulate the consumption of oxygen, and production of carbon dioxide, moisture and heat by up to eight persons. A variety of gas analyzers and dew point sensors are used to monitor the chamber atmosphere and the process flow upstream and downstream of a test article. A robust vacuum system is needed to simulate the vacuum of space.

NASA's Digital Learning Network (DLN) reaches out to thousands of students each year through video conferencing and webcasting. As part of NASA's Strategic Plan to reach the next generation of space explorers, the DLN develops and delivers educational programs that reinforce principles in the areas of science, technology, engineering and mathematics. The DLN has created a series of live education videoconferences connecting the Desert Research and Technology Studies (RATS) field test to students across the United States. The programs are also extended to students around the world via live webcasting. The primary focus of the events is the Vision for Space Exploration. During the programs, Desert RATS engineers and scientists inform and inspire students about the importance of exploration and share the importance of the field test as it correlates with plans to return to the Moon and explore Mars. This paper describes the events that took place in September 2006.

Protecting astronauts from space radiation exposure is an important challenge for mission design and operations for future exploration-class and long-duration missions. Crew members are exposed to sporadic solar particle events (SPEs) as well as to the continuous galactic cosmic radiation (GCR). If sufficient protection is not provided the radiation risk to crew members from SPEs could be significant. To improve exposure risk estimates and radiation protection from SPEs, detailed evaluations of radiation shielding properties are required. A model using a modern CAD tool ProE™, which is the leading engineering design platform at NASA, has been developed for this purpose. For the calculation of radiation exposure at a specific site, the cosine distribution was implemented to replicate the omnidirectional characteristic of the 4π particle flux on a surface.

NASA's Digital Learning Network (DLN) reaches out to thousands of students each year through video conferencing and webcasting. The DLN has created a series of live education videoconferences connecting NASA's Extreme Environment Missions Operations (NEEMO) team to students across the United States. Programs are also extended to students around the world via live webcasting. The primary focus of the events is the vision for space exploration. During the programs, NEEMO crewmembers, including NASA astronauts, engineers and scientists, inform and inspire students about the importance of exploration and share the importance of the project as it correlates with plans to return to the moon and explore the planet Mars. These events highlight interactivity. Students talk live with the aquanauts in Aquarius, the National Oceanic and Atmospheric Administration's underwater laboratory located 4.5 kilometers off Key Largo in the Florida Keys National Marine Sanctuary.

Hollow fiber membrane reactors (HFMBRs) may be used for biological wastewater treatment, and may be integrated with NASA's current research developments. The goal of this paper is to (a) evaluate the effect of mass transfer and hydrodynamics in a microporous HFMBR and (b) appropriateness of HFMBRs for use in space applications. Even though bubble-less aeration was not achieved by the use of microporous membranes, mass transfer within the HFMBR was found to increase after biofilm formation. Conversely, convective flow dominated transport within the system. Despite the high treatment efficiency obtained by the HFMBR, due to the bioreactor size, configuration and membrane spacing within the HFMBR, the bioreactor was not a suitable option for application under microgravity conditions. Even though developing a system with more favorable system hydrodynamics would aid in treatment efficiency, the use of a microporous HFMBR is not a recommended option to meet NASA's needs.

The feasibility of a long-term space mission is partially reliant upon the ability to effectively recycle wastewater. Merged biological and physiochemical processes (integrated water recovery systems (IWRS)) are capable of producing potable water at lower equivalent system mass (ESM) than treatment systems composed of only physiochemical processes. Reducing the ESM of the water recycling units can increase the practicality of extended space missions by decreasing payload weight. In order to lower the ESM of the biological pre-treatment component, a single-stage biological reactor capable of simultaneous carbon and nitrogen removal was created by modifying the membrane-aerated biofilm reactor (MABR) design. Studies were performed in order to evaluate the water quality performance of this reactor.

Hollow fiber membranes aerate wastewater without bubble formation by separating the liquid and gases phases with a semi-permeable membrane. These membranes have shown to successfully create aerobic conditions within a biological reactor. This research investigated the effect of long term usage and biofilm growth on membrane's ability to transfer oxygen to solution. Results show that oxygen transfer across the membrane decreased significantly compared to unused membranes in areas of high biofilm growth while low biofilm growth showed only slight decreases.

Although bioprocessors have been successfully tested in ground test experiments as primary wastewater processors [1, 2 and 3], the transition required for operation of a bioprocessor in microgravity is complicated by the absence of gravity and buoyancy-driven convection. Gases are present in the wastewater bioprocessor from numerous sources including aeration, metabolic production and operation. This paper presents an innovative approach to the delivery of metabolically-required oxygen to a bioprocessor. A bioprocessor that provides oxygen delivery and bacterial support using membranes has been developed and tested during the past two years. Bench-top laboratory results have demonstrated that Total Organic Carbon (TOC) degradation above 95%, and nitrification above 80% can be maintained, while denitrification typically ranged between 5-25% in a membrane bioprocessor system (MBS).

NASA's Constellation Program, which includes the mission objectives of establishing a permanently-manned lunar Outpost, and the exploration of Mars, poses new and unique challenges for human life support systems that will require solutions beyond the Shuttle and International Space Station state of the art systems. In particular, the requirement to support crews for extended durations at the lunar outpost with limited resource resupply capability will require closed-loop regenerative life support systems with minimal expendables. Planetary environmental conditions such as lunar dust and extreme temperatures, as well as the capability to support frequent and extended-duration Extra-vehicular Activity's (EVA's) will be particularly challenging.

A reconfigurable control system is an intelligent control system that detects faults within the system and adjusts its performance automatically to avoid mission failure, save lives, and reduce system maintenance costs. The concept was first successfully demonstrated by NASA between December 1989 and March 1990 on the F-15 flight control system (SRFCS), where software was integrated into the aircraft's digital flight control system to compensate for component loss by reconfiguring the remaining control loop. This was later adopted in the Boeing X-33. Other applications include modular robotics, reconfigurable computing structure, and reconfigurable helicopters. The motivation of this work is to test such control system designs for future long term space missions, more explicitly, the automation of life support systems.

Recovery of potable water from wastewater is essential for the success of long-term manned missions to the moon and Mars. Honeywell International and the team consisting of Thermodistillation Company (Kyiv, Ukraine) and NASA Johnson Space Center (JSC) Crew and Thermal Systems Division are developing a wastewater processing subsystem that is based on centrifugal vacuum distillation. The Wastewater Processing Cascade Distillation Subsystem (CDS) utilizes an innovative and efficient multi-stage thermodynamic process to produce purified water. The rotary centrifugal design of the system also provides gas/liquid phase separation and liquid transport under microgravity conditions. A five-stage prototype of the subsystem was built, delivered and integrated into the NASA JSC Advanced Water Recovery Systems Development Facility for development testing.

Exploration Life Support (ELS) is a technology development project under the National Aeronautics and Space Administration's (NASA) Exploration Technology Development Program. The ELS Project's goal is to develop and mature a suite of Environmental Control and Life Support System (ECLSS) technologies for potential use on human spacecraft under development in support of U.S. Space Exploration Policy. Technology development is directed at three major vehicle projects within NASA's Constellation Program: the Orion Crew Exploration Vehicle (CEV), the Altair Lunar Lander and Lunar Surface Systems, including habitats and pressurized rovers. The ELS Project includes four technical elements: Atmosphere Revitalization Systems, Water Recovery Systems, Waste Management Systems and Habitation Engineering, and two cross cutting elements, Systems Integration, Modeling and Analysis, and Validation and Testing.

Microbial control in closed environmental systems, such as those of spacecraft or proposed base missions is typically limited to disinfection in the potable water system by a strong chemical agent such as iodine or chlorine. However, biofilm growth in the environmental system tubing threatens both the sterility of the potable water distribution as well as operational problems with wastewater systems. In terrestrial systems, biofilm has been recognized for its difficulty to control and eliminate as well as resulting operational problems. In order to maintain a potable water source for crew members as well as preventing operational problems in non-sterile systems, biofilm needs to be considered during system design. While biofilm controls can limit biofilm buildup, they are typically disruptive and cannot completely eliminate biofilm. Selenium coatings have shown to prevent initial biofilm attachment as well as limit attached growth on a variety of materials.