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After several decades of human spaceflight, the community of space-faring nations has accumulated a diverse and sometimes harrowing history of toxicological events that have plagued human space endeavors almost from the very beginning. Some lessons have been learned in ground-based test beds and others were discovered the hard way - when human lives were at stake in space. From such lessons one can build a risk-management framework for toxicological events to minimize the probability of a harmful exposure, while recognizing that we cannot predict all possible events. Space toxicologists have learned that relatively harmless compounds can be converted by air revitalization systems into compounds that cause serious harm to the crew.

A system performance study on a portable life support system being developed for use in the Weightless Environment Training Facility (WETF) and the Neutral Buoyancy Laboratory (NBL) has been completed. The Neutral Buoyancy Portable Life Support System (NBPLSS) will provide life support to suited astronauts training for extravehicular activity (EVA) under water without the use of umbilicals. The basic configuration is characterized by the use of medium pressure (200 - 300 psi) cryogen (liquid nitrogen/oxygen mixture) which provides cooling within the Extravehicular Mobility Unit (EMU), the momentum which enables flow in the vent loop, and oxygen for breathing. NBPLSS performance was analyzed by using a modified Metabolic Man program to compare competing configurations. Maximum sustainable steady state metabolic rates and transient performance based on a typical WETF metabolic rate profile were determined and compared.

The NASA-wide CEV Smart Buyer Team (SBT) was assembled in January 2006 and was tasked with the development of a NASA in-house design for the CEV Crew Module (CM), Service Module (SM), and Launch Abort System (LAS). This effort drew upon over 250 engineers from all of the 10 NASA Centers. In 6 weeks, this in-house design was developed. The Thermal Systems Team was responsible for the definition of the active and passive design architecture. The SBT effort for Thermal Systems can be best characterized as a design architecting activity. Proof-of-concepts were assessed through system-level trade studies and analyses using simplified modeling. This nimble design approach permitted definition of a point design and assessing its design robustness in a timely fashion. This paper will describe the architecting process and present trade studies and proposed thermal designs

An EVA simulation with a medical contingency scenario was conducted in 2006 with the NASA Haughton-Mars and EVA Physiology System and Performance Projects, to develop medical contingency management and evacuation techniques for planetary surface exploration. A rescue/evacuation system to allow two rescuer astronauts to evacuate one incapacitated astronaut was evaluated. The rescue system was utilized effectively to extract an injured astronaut up a slope of15-25° and into a surface mobility rover for transport to a simulated habitat for advanced medical care. Further research is recommended to evaluate the effects of reduced gravity and to develop synergies with other surface systems for carrying out the contingency procedures.

Carbon dioxide (CO2) removal technology development for portable life support systems (PLSS) has traditionally concentrated in the areas of solid and liquid chemical sorbents and semi-permeable membranes. Most of these systems are too heavy in gravity environments, require prohibitive amounts of consumables for operation on long term planetary missions, or are inoperable on the surface of Mars due to the presence of a CO2 atmosphere. This paper describes the effort performed to mature an innovative CO2 removal technology that meets NASA's planetary mission needs while adhering to the important guiding principles of simplicity, reliability, and operability. A breadboard cryogenic carbon dioxide scrubber for an ejector-based cryogenic PLSS was developed, designed, and tested. The scrubber freezes CO2 and other trace contaminants out of expired ventilation loop gas using cooling available from a liquid oxygen (LOX) based PLSS.

Providing water necessary to maintain life support has been accomplished in spacecraft vehicles for over forty years. This paper will investigate how previous U.S. space vehicles provided potable water. The water source for the spacecraft, biocide used to preserve the water on-orbit, water stowage methodology, materials, pumping mechanisms, on-orbit water requirements, and water temperature requirements will be discussed. Where available, the hardware used to provide the water and the general function of that hardware will also be detailed. The Crew Exploration Vehicle (CEV or Orion) water systems will be generically discussed to provide a glimpse of how similar they are to water systems in previous vehicles. Conclusions, questions, and recommendations on strategies that could be applied to CEV based on previous spacecraft water system lessons learned will be made.

Development of new air revitalization system (ARS) technology can initially be performed in a subscale laboratory environment, but in order to advance the maturity level, the technology must be tested in an end-to-end integrated environment. The Air Revitalization Technology Evaluation Facility (ARTEF) at the NASA Johnson Space Center (JSC) serves as a ground test bed for evaluating emerging ARS technologies in an environment representative of spacecraft atmospheres. At the center of the ARTEF is a hypobaric chamber which serves as a sealed atmospheric chamber for closed loop testing. A Human Metabolic Simulator (HMS) was custom-built to simulate the consumption of oxygen, and production of carbon dioxide, moisture and heat by up to eight persons. A variety of gas analyzers and dew point sensors are used to monitor the chamber atmosphere and the process flow upstream and downstream of a test article. A robust vacuum system is needed to simulate the vacuum of space.

NASA's Digital Learning Network (DLN) reaches out to thousands of students each year through video conferencing and webcasting. As part of NASA's Strategic Plan to reach the next generation of space explorers, the DLN develops and delivers educational programs that reinforce principles in the areas of science, technology, engineering and mathematics. The DLN has created a series of live education videoconferences connecting the Desert Research and Technology Studies (RATS) field test to students across the United States. The programs are also extended to students around the world via live webcasting. The primary focus of the events is the Vision for Space Exploration. During the programs, Desert RATS engineers and scientists inform and inspire students about the importance of exploration and share the importance of the field test as it correlates with plans to return to the Moon and explore Mars. This paper describes the events that took place in September 2006.

Protecting astronauts from space radiation exposure is an important challenge for mission design and operations for future exploration-class and long-duration missions. Crew members are exposed to sporadic solar particle events (SPEs) as well as to the continuous galactic cosmic radiation (GCR). If sufficient protection is not provided the radiation risk to crew members from SPEs could be significant. To improve exposure risk estimates and radiation protection from SPEs, detailed evaluations of radiation shielding properties are required. A model using a modern CAD tool ProE™, which is the leading engineering design platform at NASA, has been developed for this purpose. For the calculation of radiation exposure at a specific site, the cosine distribution was implemented to replicate the omnidirectional characteristic of the 4π particle flux on a surface.

NASA's Digital Learning Network (DLN) reaches out to thousands of students each year through video conferencing and webcasting. The DLN has created a series of live education videoconferences connecting NASA's Extreme Environment Missions Operations (NEEMO) team to students across the United States. Programs are also extended to students around the world via live webcasting. The primary focus of the events is the vision for space exploration. During the programs, NEEMO crewmembers, including NASA astronauts, engineers and scientists, inform and inspire students about the importance of exploration and share the importance of the project as it correlates with plans to return to the moon and explore the planet Mars. These events highlight interactivity. Students talk live with the aquanauts in Aquarius, the National Oceanic and Atmospheric Administration's underwater laboratory located 4.5 kilometers off Key Largo in the Florida Keys National Marine Sanctuary.

Improving the methods and priorities for the collection of Life Cycle Management information is critical to the goal of reducing life cycle environmental impacts from automobile manufacturing. Currently, such information is collected under varying protocols, creating inefficiencies for OEM's and suppliers, and casting doubt on the information's quality. Recommendations from the EPA's CSI Automobile Manufacturing Sector provide important guidance to auto companies, suppliers and other stakeholders for commonizing life cycle data collection and developing data priorities. A variety of disciplines and areas of expertise, at OEM's and suppliers, will need to cooperate in the creation of new data collection tools.

It has been widely reported that injury to the leg is the most common form of non-fatal trauma associated with motorcycle accidents. Furthermore, it has also been reported that the majority of motorcycle leg injuries resemble those experienced by pedestrians in that they do not involve crush. Rather, these injuries appear to involve only a direct impact between the leg and an opposing rigid object. Often the soft tissue of the limb is injured from the inside out in that sharp bone fragments and jagged ends lacerate the soft tissue as relative motion occurs. The complexity of understanding these results is due to a combination of impact effects, biological material properties and human geometric considerations. Our ongoing research, underway for several years, is providing the fundamental data for cadaver leg and bone impact response.

Although bioprocessors have been successfully tested in ground test experiments as primary wastewater processors [1, 2 and 3], the transition required for operation of a bioprocessor in microgravity is complicated by the absence of gravity and buoyancy-driven convection. Gases are present in the wastewater bioprocessor from numerous sources including aeration, metabolic production and operation. This paper presents an innovative approach to the delivery of metabolically-required oxygen to a bioprocessor. A bioprocessor that provides oxygen delivery and bacterial support using membranes has been developed and tested during the past two years. Bench-top laboratory results have demonstrated that Total Organic Carbon (TOC) degradation above 95%, and nitrification above 80% can be maintained, while denitrification typically ranged between 5-25% in a membrane bioprocessor system (MBS).

The Maintenance and Reliability Center (MRC) at The University of Tennessee, performs research and applies cutting-edge technology to help its member companies reduce losses caused by equipment downtime. The first MRC research project dealt with the precision alignment of rotating machinery. Controlled experiments were performed at The University of Tennessee and at the Oak Ridge Center for Electrical Machinery System Testing to clearly discern what relationships exist between motor misalignment and motor efficiency. The results of these tests show no significant correlation between misalignment and changes in efficiency when the tested couplings were operated within the manufacturer's recommended range. On-going research is investigating the relationship between alignment and bearing load.

NASA's Constellation Program, which includes the mission objectives of establishing a permanently-manned lunar Outpost, and the exploration of Mars, poses new and unique challenges for human life support systems that will require solutions beyond the Shuttle and International Space Station state of the art systems. In particular, the requirement to support crews for extended durations at the lunar outpost with limited resource resupply capability will require closed-loop regenerative life support systems with minimal expendables. Planetary environmental conditions such as lunar dust and extreme temperatures, as well as the capability to support frequent and extended-duration Extra-vehicular Activity's (EVA's) will be particularly challenging.

A reconfigurable control system is an intelligent control system that detects faults within the system and adjusts its performance automatically to avoid mission failure, save lives, and reduce system maintenance costs. The concept was first successfully demonstrated by NASA between December 1989 and March 1990 on the F-15 flight control system (SRFCS), where software was integrated into the aircraft's digital flight control system to compensate for component loss by reconfiguring the remaining control loop. This was later adopted in the Boeing X-33. Other applications include modular robotics, reconfigurable computing structure, and reconfigurable helicopters. The motivation of this work is to test such control system designs for future long term space missions, more explicitly, the automation of life support systems.

Recovery of potable water from wastewater is essential for the success of long-term manned missions to the moon and Mars. Honeywell International and the team consisting of Thermodistillation Company (Kyiv, Ukraine) and NASA Johnson Space Center (JSC) Crew and Thermal Systems Division are developing a wastewater processing subsystem that is based on centrifugal vacuum distillation. The Wastewater Processing Cascade Distillation Subsystem (CDS) utilizes an innovative and efficient multi-stage thermodynamic process to produce purified water. The rotary centrifugal design of the system also provides gas/liquid phase separation and liquid transport under microgravity conditions. A five-stage prototype of the subsystem was built, delivered and integrated into the NASA JSC Advanced Water Recovery Systems Development Facility for development testing.

Exploration Life Support (ELS) is a technology development project under the National Aeronautics and Space Administration's (NASA) Exploration Technology Development Program. The ELS Project's goal is to develop and mature a suite of Environmental Control and Life Support System (ECLSS) technologies for potential use on human spacecraft under development in support of U.S. Space Exploration Policy. Technology development is directed at three major vehicle projects within NASA's Constellation Program: the Orion Crew Exploration Vehicle (CEV), the Altair Lunar Lander and Lunar Surface Systems, including habitats and pressurized rovers. The ELS Project includes four technical elements: Atmosphere Revitalization Systems, Water Recovery Systems, Waste Management Systems and Habitation Engineering, and two cross cutting elements, Systems Integration, Modeling and Analysis, and Validation and Testing.

NASA's Constellation Program includes the Orion, Altair, and Lunar Surface Systems (LSS) project offices. The first two elements, Orion and Altair, are manned space vehicles while the third element is broader and includes several subelements including Rovers and a Lunar Habitat. The upcoming planned missions involving these systems and vehicles include several risks and design challenges. Due to the unique thermal environment, many of these risks and challenges are associated with the vehicles' thermal control system. NASA's Exploration Systems Mission Directorate (ESMD) includes the Exploration Technology Development Program (ETDP). ETDP consists of several technology development projects. The project chartered with mitigating the aforementioned risks and design challenges is the Thermal Control System Development for Exploration Project.

With the Preliminary Design Review (PDR) for the Orion Crew Exploration Vehicle planned to be completed in 2009, Exploration Life Support (ELS), a technology development project under the National Aeronautics and Space Administration's (NASA) Exploration Technology Development Program, is focusing its efforts on needs for human lunar missions. The ELS Project's goal is to develop and mature a suite of Environmental Control and Life Support System (ECLSS) technologies for potential use on human spacecraft under development in support of U.S. Space Exploration Policy. ELS technology development is directed at three major vehicle projects within NASA's Constellation Program (CxP): the Orion Crew Exploration Vehicle (CEV), the Altair Lunar Lander and Lunar Surface Systems, including habitats and pressurized rovers.