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After several decades of human spaceflight, the community of space-faring nations has accumulated a diverse and sometimes harrowing history of toxicological events that have plagued human space endeavors almost from the very beginning. Some lessons have been learned in ground-based test beds and others were discovered the hard way - when human lives were at stake in space. From such lessons one can build a risk-management framework for toxicological events to minimize the probability of a harmful exposure, while recognizing that we cannot predict all possible events. Space toxicologists have learned that relatively harmless compounds can be converted by air revitalization systems into compounds that cause serious harm to the crew.

The NASA-wide CEV Smart Buyer Team (SBT) was assembled in January 2006 and was tasked with the development of a NASA in-house design for the CEV Crew Module (CM), Service Module (SM), and Launch Abort System (LAS). This effort drew upon over 250 engineers from all of the 10 NASA Centers. In 6 weeks, this in-house design was developed. The Thermal Systems Team was responsible for the definition of the active and passive design architecture. The SBT effort for Thermal Systems can be best characterized as a design architecting activity. Proof-of-concepts were assessed through system-level trade studies and analyses using simplified modeling. This nimble design approach permitted definition of a point design and assessing its design robustness in a timely fashion. This paper will describe the architecting process and present trade studies and proposed thermal designs

Providing water necessary to maintain life support has been accomplished in spacecraft vehicles for over forty years. This paper will investigate how previous U.S. space vehicles provided potable water. The water source for the spacecraft, biocide used to preserve the water on-orbit, water stowage methodology, materials, pumping mechanisms, on-orbit water requirements, and water temperature requirements will be discussed. Where available, the hardware used to provide the water and the general function of that hardware will also be detailed. The Crew Exploration Vehicle (CEV or Orion) water systems will be generically discussed to provide a glimpse of how similar they are to water systems in previous vehicles. Conclusions, questions, and recommendations on strategies that could be applied to CEV based on previous spacecraft water system lessons learned will be made.

An integrated water recovery system was operated for 91 days in support of the Lunar Mars Life Support Test Project (LMLSTP) Phase III test. The system combined both biological and physical-chemical processes to treat a combined wastewater stream consisting of waste hygiene water, urine, and humidity condensate. Biological processes were used for primary degradation of organic material as well as for nitrification of ammonium in the wastewater. Physical-chemical systems removed inorganic salts from the water and provided post-treatment. The integrated system provided potable water to the crew throughout the test. This paper describes the water recovery system and reviews the performance of the system during the test.

A system of amine-based carbon dioxide (CO2) and water vapor sorbent in pressure-swing regenerable beds has been developed by Hamilton Sundstrand and is baselined for the Orion Atmosphere Revitalization System (ARS). In two previous years at this conference, reports were presented on extensive Johnson Space Center (JSC) testing of the technology, which was performed in a representative environment with simulated human metabolic loads. The next step in developmental testing at JSC was to use real human loads in the spring of 2008.

In the design of a new space suit it is necessary to have requirements that define what mobility space suit joints should be capable of achieving in both a system and at the component level. NASA elected to divide mobility into its constituent parts -- range of motion (ROM) and torque -- in an effort to develop clean design requirements that limit subject performance bias and are easily verified. Unfortunately, the measurement of mobility can be difficult to obtain. Current technologies, such as the Vicon motion capture system, allow for the relatively easy benchmarking of range of motion (ROM) for a wide array of space suit systems. The ROM evaluations require subjects in the suit to accurately evaluate the ranges humans can achieve in the suit. However, when it comes to torque, there are significant challenges for both benchmarking current performance and writing requirements for future suits.

The International Space Station (ISS) Active Thermal Control System (ATCS) (Ref. 1,2) has changed over the past several years to address problems and to improve its assembly and operation on-orbit. This paper captures the ways in which the Internal (I) ATCS and External (E) ATCS have changed design characteristics and operations both for the system currently operating on-orbit and the new elements of the system that are about to be added and/or activated. The rationale for changes in ATCS design, assembly and operation will provide insights into the lessons learned during ATCS development. The state of the assembly of the integrated ATCS will be presented to provide a status of the build-up of the system. The capabilities of the on-orbit system will be presented with a summary of the elements of the ISS ATCS that are functional on-orbit plus the plans for launch of remaining parts of the integrated ISS ATCS.

Bioregenerative life support systems (BLSS) may be necessary for long-term space missions due to the high costs of lifting supplies and equipment into orbit. Much of the recycling to be done in a BLSS involves microbial activity. Although most studies to date have used a culture-based approach to characterize bacteria in BLSS under development, recently work has begun utilizing non-culture-based, DNA approaches to elucidate which microbes are present. In this study, we investigated whether replicate reactors develop replicate microbial communities using a 16S rRNA gene approach and terminal restriction length polymorphism analysis for tubular, nitrifier reactors in use at JSC. Our result suggests that both individual reactor and temporal signals can be detected in the microbial populations. This information may lead to optimization of inoculation procedures and reactor operations conditions to increase predictability and reliability of biological systems.

Biological water processors are currently being developed for application in microgravity environments. Work has been performed to develop a single-phase, gravity independent anoxic denitrification reactor for organic carbon removal [1]. As a follow on to this work it was necessary to develop a gravity independent nitrification reactor in order to provide sufficient nitrite and nitrate to the organic carbon oxidation reactor for the complete removal of organic carbon. One approach for providing the significant amounts of dissolved oxygen required for nitrification is to require the biological reactor design to process two-phase gas and liquid in micro-gravity. This paper addresses the design and test results overview for development of a tubular, two-phase, gravity independent nitrification biological water processor.

Since the early 1980’s, the Shuttle Extra Vehicular Activity (EVA) glove design has evolved to meet the challenge of space based tasks. These tasks have typically been satellite retrieval and repair or EVA based flight experiments. With the start of the International Space Station (ISS) assembly, the number of EVA based missions is increasing far beyond what has been required in the past; this has commonly been referred to as the “Wall of EVA’s”. To meet this challenge, it was determined that the evolution of the current glove design would not meet future mission objectives. Instead, a revolution in glove design was needed to create a high performance tool that would effectively increase crewmember mission efficiency. The results of this effort have led to the design, certification and implementation of the Phase VI EVA glove into the Shuttle flight program.

This paper provides an overview of the IMMWPS Integrated Ground Test Program, completed at the NASA Johnson Space Center (JSC) during October and November 2001. The JSC Crew and Thermal Systems Division (CTSD) has developed the IMMWPS orbital flight experiment to test the feasibility of a microbe-based water purifier for use in zero-gravity conditions. The IMMWPS design utilizes a Microbial Processor Assembly (MPA) inoculated with facultative anaerobes to convert organic contaminants in wastewater to carbon dioxide and biomass. The primary purpose of the ground test program was to verify functional operations and procedures. A secondary objective was to provide initial ground data for later comparison to on-orbit performance. This paper provides a description of the overall test program, including the test article hardware and the test sequence performed to simulate the anticipated space flight test program. In addition, a summary of significant results from the testing is provided.

The International Space Station Waste Collector Subsystem Risk Mitigation Experiment (ISS WCS RME) was flown as the primary (Shuttle) WCS on Space Shuttle flight STS-104 (ISS-7A) in July 2001, to validate new design enhancements. In general, the WCS is utilized for collecting, storing, and compacting fecal & associated personal hygiene waste, in a zero gravity environment. In addition, the WCS collects and transfers urine to the Shuttle waste storage tank. All functions are executed while controlling odors and providing crew comfort. The ISS WCS previously flew on three Shuttle flights as the Extended Duration Orbiter (EDO) WCS, as it was originally designed to support extended duration Space Shuttle flights up to 30 days in length. Soon after its third flight, the Space Shuttle Program decided to no longer require 30 day extended mission duration capability and provided the EDO WCS to the ISS Program.

Conceptual designs for a space suit Personal Life Support Subsystem (PLSS) were developed and assessed to determine if upgrading the system using new, emerging, or projected technologies to fulfill basic functions would result in mass, volume, or performance improvements. Technologies were identified to satisfy each of the functions of the PLSS in three environments (zero-g, Lunar, and Martian) and in three time frames (2006, 2010, and 2020). The viability of candidate technologies was evaluated using evaluation criteria such as safety, technology readiness, and reliability. System concepts (schematics) were developed for combinations of time frame and environment by assigning specific technologies to each of four key functions of the PLSS -- oxygen supply, waste removal, thermal control, and power. The PLSS concepts were evaluated using the ExtraVehicular Activity System Sizing Analysis Tool, software created by NASA to analyze integrated system mass, volume, power and thermal loads.

A small team of NASA engineers has been assembled at the Johnson Space Center, with the goal of developing an inexpensive space-capable vehicle. In order to minimize cost and development time of the experimental vehicle, it was desirable to build upon a previously-developed vehicle shape. The basic shape of the X-24A experimental lifting body was chosen for several reasons, and in the case of the Environmental Control and Life Support (ECLS), the de-orbit cross-range capability of this shape provides for a minimal on-orbit time while waiting for landing opportunities, which in turn simplifies the ECLS. Figure 1 shows the X-38 vehicle body shape. In keeping with the goal of rapidly developing an inexpensive and reliable vehicle, the ECLS was developed using simple, passive systems where practical. This paper provides an overview of the ECLS mission requirements and design, with emphasis on the philosophy used in its development.

Biological wastewater processing has been under investigation by AlliedSignal Aerospace and NASA Johnson Space Center (JSC) for future use in space. Testing at JSC in the Hybrid Regenerative Water Recovery System (HRWRS) in preparation for future closed human testing has been performed. Computer models have been developed to aid in the design of a new four-person immobilized cell bioreactor. The design of the reactor and validation of the computer model is presented. In addition, the total organic carbon (TOC) computer model has been expanded to begin investigation of nitrification. This model is being developed to identify the key parameters of the nitrification process, and to improve the design and operating conditions of nitrifying bioreactors. In addition, the model can be used as a design tool to rapidly predict the effects of changes in operational conditions and reactor design, significantly reducing the number and duration of experiments required.

Research committed by the Langley Research Center through 1995 resulting in the HZETRN code provides the current basis for shield design methods according to NASA STD-3000 (2005). With this new prominence, the database, basic numerical procedures, and algorithms are being re-examined with new methods of verification and validation being implemented to capture a well defined algorithm for engineering design processes to be used in this early development phase of the Bush initiative. This process provides the methodology to transform the 1995 HZETRN research code into the 2005 HZETRN engineering code to be available for these early design processes. In this paper, we will review the basic derivations including new corrections to the codes to insure improved numerical stability and provide benchmarks for code verification.

For over 40 years, NASA has been putting humans safely into space in part by minimizing microbial risks to crew members. Success of the program to minimize such risks has resulted from a combination of engineering and design controls as well as active monitoring of the crew, food, water, hardware, and spacecraft interior. The evolution of engineering and design controls is exemplified by the implementation of HEPA filters for air treatment, antimicrobial surface materials, and the disinfection regimen currently used on board the International Space Station. Data from spaceflight missions confirm the effectiveness of current measures; however, fluctuations in microbial concentrations and trends in contamination events suggest the need for continued diligence in monitoring and evaluation as well as further improvements in engineering systems. The knowledge of microbial controls and monitoring from assessments of past missions will be critical in driving the design of future spacecraft.

Supply of oxygen (O2) and hydrogen (H2) by electrolyzing water in space will play an important role in meeting the National Aeronautics and Space Administration's (NASA's) needs and goals for future space missions. Both O2 and H2 are envisioned to be used in a variety of processes including crew life support, spacecraft propulsion, extravehicular activity, electrical power generation/storage as well as in scientific experiment and manufacturing processes. Life Systems, Inc., in conjunction with NASA, has been developing an alkaline-based Static Feed Electrolyzer (SFE). During the development of the water electrolysis technology over the past 23 years, an extensive engineering and scientific data base has been assembled.

Two simulated spacecraft water systems are being used to evaluate the effectiveness of iodine for controlling microbial contamination within such systems. An iodine concentration of about 2.0 mg/L is maintained in one system by passing ultrapure water through an iodinated ion exchange resin. Stainless steel coupons with electropolished and mechanically-polished sides are being used to monitor biofilm formation. Results after three years of operation show a single episode of significant bacterial growth in the iodinated system when the iodine level dropped to 1.9 mg/L. This growth was apparently controlled by replacing the iodinated ion exchange resin, thereby increasing the iodine level. The second batch of resin has remained effective in controlling microbial growth down to an iodine level of 1.0 mg/L. Scanning electron microscopy indicates that the iodine has impeded but may have not completely eliminated the formation of biofilm.

Controlling microbial growth and biofilm formation in spacecraft water-distribution systems is necessary to protect the health of the crew. Methods to decontaminate the water system in flight may be needed to support long-term missions. We evaluated the ability of iodine and ozone to kill attached bacteria and remove biofilms formed on stainless steel coupons. The biofilms were developed by placing the coupons in a manifold attached to the effluent line of a simulated spacecraft water-distribution system. After biofilms were established, the coupons were removed and placed in a treatment manifold in a separate water treatment system where they were exposed to the chemical treatments for various periods. Disinfection efficiency over time was measured by counting the bacteria that could be recovered from the coupons using a sonication and plate count technique. Scanning electron microscopy was also used to determine whether the treatments actually removed the biofilm.