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Long-term manned operation of NASA's Space Station will dictate use of regenerative processes for the revitalization of the Spacecraft atmosphere. An alkaline Static Feed Water Electrolysis System (SFWES) is being developed by Life Systems, Inc. and NASA to generate metabolic oxygen (O2) for the crew, provide hydrogen (H2) for reduction of concentrated carbon dioxide (CO2) and compensate for O2 lost overboard due to Space Station leakage. The SFWES employs highly efficient electrodes with rugged unitized cell construction. Integrated mechanical components and advanced automated Control/Monitor Instrumentation (C/M I) are used to reduce system complexity while enhancing overall reliability and maintainability. Crew size and the unique environment of space drive the system design.