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The on-demand production of Medical Grade Water (MGW) is a critical biomedical requirement for future long-duration exploration missions. Potentially, large volumes of MGW may be needed to treat burn victims, with lesser amounts required to reconstitute pharmacological agents for medical preparations and biological experiments, and to formulate parenteral fluids during medical treatment. Storage of MGW is an untenable means to meet this requirement, as are nominal MGW production methods, which use a complex set of processes to remove chemical contaminants, inactivate all microorganisms, and eliminate endotoxins, a toxin originating from gram-negative bacteria cell walls. An innovative microgravity compatible alternative, using a microwave-based MGW generator, is described in this paper. The MGW generator efficiently couples microwaves to a single-phase flowing stream, resulting in super-autoclave temperatures.

Packed bed reactors are well known for their vast and diverse applications in the chemical industry; from gas absorption, to stripping, to catalytic conversion. Use of this type of reactor in terrestrial applications has been rather extensive because of their simplicity and relative ease of operation. Developing similar reactors for use in microgravity is critical to many space-based advanced life support systems. However, the hydrodynamics of two-phase flow packed bed reactors in this new environment and the effects of one physicochemical process on another has not been adequately assessed. Surface tension or capillary forces play a much greater role which results in a shifting in flow regime transitions and pressure drop. Results from low gravity experiments related to flow regimes and two-phase pressure drop models are presented in this paper along with a description of plans for a flight experiment on the International Space Station (ISS).