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New and derivative commercial jetliner programs face increased pressure to reduce cost, shorten development cycles, increase production rates, and create an increasingly fuel efficient aircraft. The industry also has limited engineering resources and suppliers with manufacturing capacity constraints. Designing parts right the first time, while concurrently taking into account available and proven manufacturing techniques, is crucial to meeting product development schedule and profitability goals. New, knowledge-based software solutions bridge the gap between design, manufacturing, and the supply chain, assuring timely, cost effective, and correctly manufactured products. Boeing Commercial Airplanes used a unique knowledge-based software solution to analyze one of the most complicated jetliner parts: the titanium part joining the wing to the aircraft body.