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The Spacelab Life Sciences 2 mission (SLS-2) is the second in a planned series of dedicated Life Sciences missions utilizing the European Space Agency-provided Spacelab module. The mission, tentatively scheduled for a mid-1992 launch, will comprise a total of eighteen experiments encompassing both human and animal research. Eight of the eighteen experiments will involve animal life sciences research and will be managed by the Space Life Sciences Payloads Office (SLSPO) at NASA's Ames Research Center (ARC). The ARC payload complement of eight experiments will include six which use rodents and two which use primates (squirrel monkeys). SLS-2 provides an opportunity for even more extensive investigations into the effects of weightlessness upon the anatomy and physiology of rodent and primate systems.