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The cabin space of the Columbus APM is well ventilated by air entering through multiple air diffusers and exiting via the return grid and hatch. Therefore, the heat transfers by bulk fluid motion and by convection to the walls need to be experimentally and/or numerically investigated and implemented in the thermal mathematical models (TMM) describing the cabin. CFD analysis provided key data on the thermal couplings due to convective heat transfer and bulk fluid motion for the thermal mathematical model, which in turn was used to correlate test data from an environmental control system test and to provide supplemental information on assumptions used in the lumped capacitance model. This paper presents the logic and results of the steady-state CFD analysis, the potential implementation of the results in a thermal mathematical model, and compares these results with test data obtained during a separate Columbus cabin ventilation qualification test.