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Development of bioreactor technology for a regenerative life support primary water processor is ongoing by a team, composed of NASA and major aerospace companies, using a concurrent integrated approach. This approach consists of performing small-scale reactor experimental investigations, large-scale experimental studies, and computer modeling efforts on both the bioprocessor subsystem level and on the integrated water recovery system level. Bench-top experimental studies are aimed at developing an understanding of the biological process and the effect of key parameters on the process, determining the operational envelope for the regenerative life support application, and addressing process control issues. The large-scale experimental studies, in which a bioprocessor is one subsystem of an overall water recovery system, address the full-scale system integration and operational issues.