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There are many parameters which influence the maintainability of long duration manned space flights. This study involved a detailed investigation of the sensitivity of some of the major parameters on a typical 1975 near earth orbit spacecraft and mission. A mechanized analytical math model and a mission simulation model were utilized to evaluate the effects of: spacecraft system weight, volume and reliability; mission duration and resupply rate; and maintenance requirements on the total spacecraft requirements to achieve various probabilities of crew survival and mission success. Preliminary information developed in the NAS 2-3705 contract is presented. The results obtained to date are given, but specific conclusions will not be made until the study is completed.