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It is well known that rotational loading is responsible for a spectrum of diffuse brain injuries spanning from concussion to diffuse axonal trauma. Many experimental studies have been performed to understand the pathological and biomechanical factors associated with diffuse brain injuries. Finite element models have also been developed to correlate experimental findings with intrinsic variables such as strain. However, a paucity of studies exists examining the combined role of the strain-time parameter. Consequently, using the principles of finite element analysis, the present study introduced the concept of sustained maximum principal strain (SMPS) criterion and explored its potential applicability to diffuse brain injury. An algorithm was developed to determine if the principal strain in a finite element of the brain exceeded a specified magnitude over a specific time interval.

In this study, three-dimensional nonlinear finite element models of age-specific one year old, three year old, and six year old pediatric human cervical spine (C4-C5-C6) structures were developed. Their biomechanical responses were compared with the adult human cervical spine behavior under different loadings and at all load levels. The adult human cervical spine model was constructed from close-up computed tomography sections in the axial and sagittal planes, and sequential anatomic cryomicrotome sections. The adult model was validated with experimental moment-rotation data under flexion-extension and compression by correlating bilateral strains in the vertebral body and the lateral masses, and the force-deflection responses with experiments conducted in our laboratory. The adult model was modified to create one, three and six year old pediatric spines by incorporating the local geometrical and material characteristics of the developmental anatomy.

Lower extremity injuries caused by floor plate impacts through the axis of the lower leg are a major source of injury and disability for civilian and military vehicle occupants. A collection of PMHS pendulum impacts was revisited to obtain data for paired booted/unbooted test on the same leg. Five sets of paired pendulum impacts (10 experiments in total) were found using four lower legs from two PMHS. The PMHS size and age was representative of an average young adult male. In these tests, a PMHS leg was impacted by a 3.4 or 5.8 kg pendulum with an initial velocity of 5, 7, or 10 m/s (42-288 J). A matching LS-DYNA finite element model was developed to replicate the experiments and provide additional energy, strain, and stress data. Simulation results matched the PMHS data using peak values and CORA curve correlations. Experimental forces ranged between 1.9 and 12.1 kN experimentally and 2.0 and 11.7 kN in simulation.

Spinal trauma produced from motor vehicle accidents, diving accidents, or falls occur at high rates of loading. This study was undertaken to reproduce clinically relevant cervical spine injuries under controlled conditions. Six isolated head - T2 human cadaveric preparations were tested using an electrohydraulic piston actuator at loading rates from 295 to 813 cm/sec. The Hybrid III head-neck was tested similarly at rates from 401 to 683 cm/sec. The input forces for specimen tests were of higher magnitude and shorter duration than the distally measured forces. In contrast, the Hybrid III head-neck revealed similar magnitude and duration force traces from input to output. The specimen preparations were analyzed kinematically at 1200 frames/sec with 20 to 30 retroreflective targets fixed to each level of the cervical spine. With this technique it is possible to temporally follow cervical damage as a function of applied force.

Head injury is a serious threat to lives of people working around farm machinery. The consequence of head injuries are costly, paralytic, and often fatal. Clinical and biomechanical data on head injuries are reviewed and their application in the analysis of head injury risk associated with farm tractor discussed. A significant proportion of tractor-related injuries and deaths to adults, as well as children, is due directly or indirectly to head injury. An improved injury reporting program and biomechanical studies of human response to tractor rollover, runover, and falls, are needed to understand mechanisms of the associated head injury.

A new anthropomorphic test device (ATD) is being developed by the US Army to be responsive to vertical loading during a vehicle underbody blast event. To obtain design parameters for the new ATD, a series of non-injurious tests were conducted to derive biofidelity response corridors for the foot-ankle complex under vertical loading. Isolated post mortem human surrogate (PMHS) lower leg specimens were tested with and without military boot and in different initial foot-ankle positions. Instrumentation included a six-axis load cell at the proximal end, three-axis accelerometers at proximal and distal tibia, and calcaneus, and strain gages. Average proximal tibia axial forces for a neutral-positioned foot were about 2 kN for a 4 m/s test, 4 kN for 6 m/s test and 6 kN for an 8 m/s test. The force time-to-peak values were from 3 to 5 msec and calcaneus acceleration rise times were 2 to 8 msec.

The objective of the study was to investigate the biomechanical response of the intact cranium. Unembalmed human cadavers were used in the study. The specimens were transected at the base of the skull leaving the intracranial contents intact; x-ray and computed tomography (CT) scans were obtained. They were fixed in a specially designed frame at the auditory meatus level and placed on the platform of an electrohydraulic testing device via a six-axis load cell. Following radiography, quasistatic loading to failure was applied to one of the following sites: frontal, vertex, parietal, temporal, or occipital. Retroreflective targets were placed in two mutually orthogonal planes to record the localized temporal kinematics. Applied load and piston displacement, and the output generalized force (and moment) histories were recorded using a modular digital data acquisition system. After the test, x-ray and CT images were obtained, and defleshing was done.

Inertial loading of the head-neck complex occurs in rear impacts wherein the head and neck of the occupant are initially subjected to rearward forces. Epidemiological evidence exists to demonstrate the significance and societal impact of these injuries [4]. From a clinical perspective, trauma secondary to inertial loads belongs to the lower end of the Abbreviated Injury Scale, and no specific diagnostic techniques are available to quantitatively document the injury. Furthermore, identification of the mechanisms of injury and derivation of injury thresholds are limited. In fact, there is a paucity of literature focusing on the reproduction of rear impact-induced neck injuries due to a single-event rear impact. Because the impact acceleration is transmitted to the head from the torso via the cervical column, the components of the human neck play a role in the mechanics of trauma.

Because of the need to evaluate anthropomorphic test device (ATD) biofidelity under high-head angular accelerations, the purpose of the present investigation was to develop appropriate instrumentation for intact post mortem human subject (PMHS) testing, validate the instrumentation, and obtain information to characterize the response of the head-neck complex under this loading scenario. A series of rigid-arm pendulum, inertially loaded ATD tests was conducted. Head and neck ATD hydraulic piston chin pull tests were conducted. Subsequently, a series of PMHS tests was conducted to derive the response of the human head-neck under high-rate chin loading. Finally, Hybrid III and THOR-NT ATD head-neck systems were evaluated under the same scenario as the PMHS. A parametric analysis for center of gravity (CG) location and accelerometer orientation determined that even small errors (± 3 mm or 2 degrees), produced errors in the force and moment calculations by as much as 17%.

Injury to the far side occupant has been demonstrated as a significant portion of the total trauma in side impacts. The objective of the study was to determine the response of PMHS in far side impact configurations, with and without generic countermeasures, and compare responses to the WorldSID and THOR dummies. A far side impact buck was designed for a sled test system that included a center console and three-point belt system. The buck allowed for additional options of generic countermeasures including shoulder or thorax plates or an inboard shoulder belt. The entire buck could be mounted on the sled in either a 90-degree (3-o'clock PDOF) or a 60-degree (2-o'clock PDOF) orientation. A total of 18 tests on six PMHS were done to characterize the far side impact environment at both low (11 km/h) and high (30 km/h) velocities. WorldSID and THOR-NT tests were completed in the same configurations to conduct matched-pair comparisons.

Injury to the far side occupant has been demonstrated as a significant portion of the total trauma in side impacts. The objective of the study was to determine the response of PMHS in far side impact configurations, with and without generic countermeasures, and compare responses to the WorldSID and THOR dummies. A far side impact buck was designed for a sled test system that included a center console and three-point belt system. The buck allowed for additional options of generic countermeasures including shoulder or thorax plates or an inboard shoulder belt. The entire buck could be mounted on the sled in either a 90-degree (3-o'clock PDOF) or a 60-degree (2-o'clock PDOF) orientation. A total of 18 tests on six PMHS were done to characterize the far side impact environment at both low (11 km/h) and high (30 km/h) velocities. WorldSID and THOR-NT tests were completed in the same configurations to conduct matched-pair comparisons.

Forty-two side impact cadaver sled tests were conducted at 24 and 32 km/h impact speeds into rigid and padded walls. The post-mortem human subjects were instrumented with accelerometers on the ribs and spine and chest bands around the thorax and abdomen to characterize their mechanical response during the impact. Load cells at the wall measured the impact force at the level of the thorax, abdomen, pelvis, and lower extremities. The resulting injuries were determined through detailed autopsy and radiography. Rib fractures with or without associated hemo/pneumo thorax or flail chest were the most common injury with severity ranging from AIS=0 to 5. Full and half thorax deflections were computed from the chest band data. The cadaver test data was analyzed using ANOVA and logistic regression. The age of the subject at the time of death had influence on injury outcome while gender and mass of the subject had little or no influence on injury outcome.

Axial loading of the calcaneus-talus-tibia complex is an important injury mechanism for moderate and severe vehicular foot-ankle trauma. To develop a more definitive and quantitative relationship between biomechanical parameters such as specimen age, axial force, and injury, dynamic axial impact tests to isolated lower legs were conducted at the Medical College of Wisconsin (MCW). Twenty-six intact adult lower legs excised from unembalmed human cadavers were tested under dynamic loading using a mini-sled pendulum device. The specimens were prepared, pretest radiographs were taken, and input impact and output forces together with the pathology were obtained using load cell data. Input impact forces always exceeded the forces recorded at the distal end of the preparation. The fracture forces ranged from 4.3 to 11.4 kN.

During certain events such as underbody blasts due to improvised explosive devices, occupants in military vehicles are exposed to inferior-to-superior loading from the pelvis. Injuries to the pelvis-sacrum-lumbar spine complex have been reported from these events. The mechanism of load transmission and potential variables defining the migration of injuries between pelvis and or spinal structures are not defined. This study applied inferior-to-superior impacts to the tuberosities of the ischium of supine-positioned five post mortem human subjects (PMHS) using different acceleration profiles, defined using shape, magnitude and duration parameters. Seventeen tests were conducted. Overlay temporal plots were presented for normalized (impulse momentum approach) forces and accelerations of the sacrum and spine.

Engineering efforts directed at better occupant safety require a thorough understanding of available epidemiologic data. Epidemiologic studies using clinical as well as accident information facilitates the prioritization of biomechanics research so that controlled laboratory experimentation and/or analytical models can be advanced. This information has also value in dictating levels and types of injury that are critical to the development of anthropomorphic test devices used in crash environments. In this paper, motor vehicle accident related (excluding pedestrians, bicyclists, and motorcyclists) epidemiologic data were obtained from clinical and computerized accident (National Accident Sampling System-NASS) files. Clinical data were gathered from patients admitted to the Medical College of Wisconsin Affiliated Hospitals, and fatalities occurring in Milwaukee County, State of Wisconsin. NASS database with specific focus on spinal injuries of motor vehicle occupants was also used.

The purpose of this study was to determine scale factors for small, mid-size and large adults using a caprine model. In a previous study conducted in our lab, scaling relationships were developed to define cervical spine tolerance values of children using caprine specimens. In that study, tolerances were normalized with respect to an average adult. Because airbag-related injuries are associated with out-of-position children and small adult females, additional experimental data are needed to better estimate human tolerance. In the present study, cervical spine radiographs from the 5th, 50th and 95th percentile human adults were used to determine vertebral body heights for small, mid-size and large anthropometries. Mean human vertebral body heights were computed for each anthropometry and were normalized with respect to mid-size anthropometry.

This study was conducted to quantify intracranial biomechanical responses and external blast overpressures using physical head model to understand the biomechanics of blast traumatic brain injury and to provide experimental data for computer simulation of blast-induced brain trauma. Ellipsoidal-shaped physical head models, made from 3-mm polycarbonate shell filled with Sylgard 527 silicon gel, were used. Six blast tests were conducted in frontal, side, and 45° oblique orientations. External blast overpressures and internal pressures were quantified with ballistic pressure sensors. Blast overpressures, ranging from 129.5 kPa to 769.3 kPa, were generated using a rigid cannon and 1.3 to 3.0 grams of pentaerythritol tetranitrate (PETN) plastic sheet explosive (explosive yield of 13.24 kJ and TNT equivalent mass of 2.87 grams for 3 grams of material).

The patho-anatomic alterations due to vertical loading of the human cervical column were documented and correlated with biomechanical kinematic data. Seven fresh human cadaveric head-neck complexes were prepared, and six-axis load cells were placed at the proximal and distal ends of the specimens to document the gross biomechanical response. Retroreflective markers were placed on bony landmarks of vertebral bodies, articular facets, and spinous processes along the entire cervical column. Targets were also placed on the occiput and arch of C1. The localized movements of these markers were recorded using a video analyzer during the entire loading cycle. Pre-test two-dimensional, and three-dimensional computerized tomography (CT), and plane radiographs were taken. The specimens were loaded to failure using an electrohydraulic testing device at a rate of 2 mm/s.

Lower cervical spine injuries are more common in survivors of motor vehicle crashes sustaining neck trauma. Injury criteria are determined using upper neck loads in dummies although a lower neck load cell exists. Due to a paucity of lower neck data from post mortem human subject (PMHS) studies, this research was designed to determine the head-neck biomechanics with a focus on lower neck metrics and injuries. Sixteen frontal impact tests were conducted using five belted PMHS. Instrumentation consisted of a pyramid-shaped nine accelerometer package on the head, tri-axial accelerometer on T1, and uniaxial accelerometer on the sled. Three-dimensional kinematics of the head-neck complex were obtained using a 20-camera high-speed motion analysis system. Testing sequence was: low (3.6 m/s), medium (6.9 m/s), repeat low, and high (15.8 m/s) velocities. Trauma evaluations were made between tests. Testing was terminated upon confirmation of injuries.

This study was conducted to collect data and gain insights relative to the mechanisms and factors involved in hip injuries during frontal crashes and to study the tolerance of hip injuries from this type of loading. Unembalmed human cadavers were seated on a standard automotive seat (reinforced) and subjected to knee impact test to each lower extremity. Varying combinations of flexion and adduction/abduction were used for initial alignment conditions and pre-positioning. Accelerometers were fixed to the iliac wings and twelfth thoracic vertebral spinous process. A 23.4-kg padded pendulum impacted the knee at velocities ranging from 4.3 to 7.6 m/s. The impacting direction was along the anteroposterior axis, i.e., the global X-axis, in the body-fixed coordinate system. A load cell on the front of the pendulum recorded the impact force. Peak impact forces ranged from 2,450 to 10,950 N. The rate of loading ranged from 123 to 7,664 N/msec. The impulse values ranged from 12.4 to 31.9 Nsec.