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Simulation of passenger compartment climatic conditions is becoming increasingly important as a complement to wind tunnel and field testing to help achieve improved thermal comfort while reducing vehicle development time and cost. Delphi Harrison Thermal Systems has collaborated with the University of California, Berkeley to develop the capability of predicting occupant thermal comfort to support automotive climate control systems. At the core of this Virtual Thermal Comfort Engineering (VTCE) technique is a model of the human thermal regulatory system based on Stolwijk’s model but with several enhancements. Our model uses 16 body segments and each segment is modeled as four body layers (core, muscle, fat, and skin tissues) and a clothing layer.