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The development of a successful fuel additive requires considerable effort, a large share of which must be expended on the effect of the additive on engine durability. Durability may be affected as soon as the fuel enters the fuel tank and the possibility of such good or bad effects continues until the exhaust gases have cleared the rear bumper. Some of the durability aspects which can be either improved or made more severe are listed, these include fuel system corrosion, carburetor and manifold deposits, combustion chamber and spark plug deposits, engine wear and general cleanliness and bearing, exhaust system and rear bumper corrosion. It is shown that of seven experimental additives tested in a fleet of passenger cars of one make operated under severe duty conditions, four additives decreased exhaust valve life while three increased exhaust valve life by from twenty-five to fifty per cent.