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The COLUMBUS pressurized modules APM and PM2 are designed for a useful lifetime of 30 years. The APM, which forms part of the International Space Station, will be permanently manned with a 3-men-crew. The PM2, which is the pressurized module of the Men-Tended-Free-Flyer (MTFF) will be manned for the servicing period of 10 days followed by a 180-day unmanned period. In order to protect the crew from contamination by hazardous substances, which may be present in the cabin air, effective contamination management is required. This consists of a contamination monitoring system to detect and measure trace gases in the cabin atmosphere, and a contamination control system to be able to maintain the concentration of each potential contaminant below the maximum allowable concentration.