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This study Investigates the response of human cadavers1, and live anesthetized and post-mortem primates and canines2, to blunt lateral thoraco-abdominal impact. There were 12 primates: 5 post-mortem and 7 live anesthetized; 10 canines; 1 post-mortem and 9 live anesthetized; and 3 human cadavers. A 10 kg free-flying mass was used to administer the impact in the right to left direction. To produce the varying degrees of injury, factors including velocity, padding of the impactor surface, location of impact site, and impactor excursion were adjusted. The injuries were evaluated by gross autopsy, and in the case of live subjects, current clinical methods such as sequential peritoneal lavage and biochemical assays were also employed. Mechanical measurements included force time history, intraortic pressure, and high-speed cineradiography to define gross organ motion.