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Sustained crew performance under conditions of isolation, confinement and increased risk is a key contributor to the success of manned space exploration missions. Measuring crew performance and identifying the factors affecting it is therefore crucial both during actual space missions and as part of precursor activities on the ground. Planetary analog bases play an important role in this context. These integrated simulation facilities allow the operational, hardware, and human side of all mission-related elements to be combined, and thus permit the capturing of interactions among these elements. The crew on board such a station is exposed to stressors and other conditions similar to those encountered during space missions. Planetary analog bases therefore represent a valuable resource for better understanding the dynamics of crew performance.