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Fuel additives are used in diesel fuel for various reasons. For example, poor lubricity of some low sulfur and ultra low sulfur fuels necessitate the addition of lubricity additives to maintain acceptable protection of fuel system components. However, with today's high pressure fuel systems and lubricant oil recycling practices, some lubricant mixing with the fuel is unavoidable. As a result, an increase in fuel filter plugging was reported when lubricant components are present in the fuel. This paper shows filter plugging resulted from the interaction of basic lubricant additives with acidic fuel additives. Attempts to reduce the plugging by supplemental fuel additives were technically successful, but not economically feasible. The linkage between filter plugging and additive interactions is demonstrated in this paper. Part II of this series will explore the mechanisms of the additive interactions, and other causes for filter plugging.