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In December 2003, fifteen participating Automobile Manufacturers announced the adoption of voluntary standards for geometric compatibility in frontal crashes. In an October 2003 report, Insurance Institute of Highway Safety (IIHS) estimated that an 8 to 28 percent fatality reduction might be achieved with better geometric and stiffness compatibility (O’Neill, 2003). This benefit was based on comparing the fatality risks of car occupants in car-to-car collisions and in car-to-SUV collisions. Reduced occupant compartment intrusion was cited as the principal advantage gained by compatibility improvements. However, the study did not actually examine the role that intrusion played in causing the fatalities. This study examines the magnitude of serious injuries in frontal crashes that could be addressed by reducing occupant compartment intrusion. Each frontal vehicle-to-vehicle case in William Lehman Injury Research Center (WLIRC) data was examined to determine the cause of each injury.