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Aftertreatment devices are exposed to exhaust poisons from fuel, oil and coolant. Studies on fuel- and lubricant-based poisoning have been widely published. However, diesel oxidation catalyst (DOC) and catalyzed soot filter (CSF) performance after exposure to constituents of coolant is not fully understood. Exhaust gas recirculation (EGR) cooler failure can cause a coolant leak into the exhaust that can reach the exhaust aftertreatment system. Coolant contains elements that can cause deterioration of aftertreatment components. This study focuses on the poisoning effect of coolant on the performance of a DOC + CSF system. The coolant introduction simulates an engine failure such as an EGR cooler internal fracture. DOC NO oxidation, quenching and hydrocarbon (HC) slip control performance during active regenerations are evaluated after slow and after consecutive fast coolant introduction and compared to the performance before the coolant exposure.