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Technical Paper

Data Censoring and Parametric Distribution Assignment in the Development of Injury Risk Functions from Biochemical Data

2004-03-08
2004-01-0317
Biomechanical data are often assumed to be doubly censored. In this paper, this assumption is evaluated critically for several previously published sets of data. Injury risk functions are compared using simple logistic regression and using survival analysis with 1) the assumption of doubly censored data and 2) the assumption of right-censored (uninjured specimens) and uncensored (injured) data. It is shown that the injury risk functions that result from these differing assumptions are not similar and that some experiments will require a preliminary assessment of data censoring prior to finalizing the experimental design. Some types of data are obviously doubly censored (e.g., chest deflection as a predictor of rib fracture risk), but many types are not left censored since injury is a force-limiting phenomenon (e.g., axial force as a predictor of tibia fracture). Guidelines for determining the censoring for various types of experiment are presented.
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