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The Direct Numerical Simulation (DNS) approach to solving the fundamental transport equations down to the smallest scales of motion is favorable should the requirement be a truly predictive solution of fluid dynamic problems, but the simulation run times are unacceptable for most practical industrial applications. Despite the steadily increasing computational capabilities, Reynolds Averaged Navier-Stokes (RANS) based frameworks remain the most commercially viable option for high volume sectors, like automotive. The sub models within RANS simplify the description of key physical phenomena and include several numerical constants. These so-called “tuning constants” introduce multivariable dependencies that are almost impossible to untangle with local sensitivity studies.