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A novel CFD simulation technique has been developed that unites realistic three-dimensional resolution of diesel particulate filter systems with computational efficiency. Three-dimensional resolution of the thermofluiddynamic behaviour during transient soot loading and regeneration is necessary for the optimization of the function, durability, weight and cost of DPF systems. Computational efficiency is required to allow its use as a standard development tool during all engineering phases and to allow the simulation of driving cycles. The detailed conclusions that can be drawn about soot distribution and thermal characteristics during the regeneration assist in ensuring the DPF function and avoiding DPF failures over the operational lifetime.