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The William Lehman Injury Research Center has conducted multi-disciplinary investigations of fifty crashes involving drivers protected by air bags. In all cases, serious injuries were suspected. Nine cases involved fatal injuries. These cases are not representative of crashes in general. However, when used in conjunction with NASS/CDS they provide insight into the most severe injuries in crashes of vehicles equipped with air bags. A comparison with data from the National Accident Sampling System; Crashworthiness Data System (NASS/CDS) shows that head injury and abdominal injury make up a larger fraction in the Lehman data than in NASS/CDS. Examination of fatal cases indicates that head injuries are frequently caused by intruding structure or by unfavorable occupant kinematics among the unrestrained population.