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This SAE Information Report provides definitions and discussions of key terms concerning driver drowsiness and fatigue, and basic information on measuring drowsiness and fatigue. It also includes information and concepts for driver drowsiness as they relate to the safe operation of a vehicle. The key driver drowsiness and fatigue causal factors include the following: (1) sleep quality and quantity, (2) time of day, (3) time awake, (4) time on task (modulated by characteristics of the driving task), (5) task-related fatigue (variations of arousal levels related to task underload and overload), and (6) combinations of these factors. Medical conditions, medication, alcohol, or drugs exacerbate drowsiness; however, the discussion in this report is limited to fatigue concepts.