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This paper investigates the use of internally lubricated and reinforced thermoplastic compounds in tribological applications requiring high pressure-velocity (P-V) performance. Elevated temperature wear testing, limiting P-V testing and elevated temperature mechanical testing demonstrate the feasibility of using internally lubricated and reinforced Polyetheretherketone and thermoplastic Polyimides in high P-V applications. The data also suggest that reinforced and lubricated Polyphenylene Sulfide and Polyphthalamide may be worth investigating as even lower cost alternatives.