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MADYMO is a well accepted multibody program for crash analyses. The main emphasis of the program is the prediction of the kinematics and dynamic behaviour of crash victims during a crash. A brief description of the MADYMO history and theory is presented as well as recently developed couplings with explicit finite element programs for non-linear structural analyses. The development of dummy databases is described with special emphasis on the development of the EUROSID dummy database using a new multibody module. This module is based on a recursive algorithm and allows modelling of other kinematic joints in addition to the currently available ball and socket joints. The use of MADYMO in impact biomechanics is illustrated with examples from the area of vehicle safety and sports biomechanics. The use of MADYMO for structural modelling is illustrated by a side-impact simulation using MADYMO to model both car and occupant.