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Compared with other applicable processes such as incineration, the catalytic wet oxidation process is considered to be the most practically applicable waste treatment process for the CELSS. In this report, the quantity of carbon monoxide generated in the wet oxidation process is identified and a measure for carbon monoxide minimization is discussed. As a result of a bench test, it became apparent that a non-negligible quantity of carbon monoxide could be generated in the catalytic wet oxidation process. However, it can be expected that this CO content will be reduced to a safe level by applying the wet oxidation process catalyst reactor to CO oxidation.