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In an attempt to make vehicle restraint systems more effective in protecting occupants, many advanced safety technologies have been introduced. These advanced technologies are mostly adaptive technologies. The ability of a restraint system to adapt itself to crash parameters like crash speed and type, occupant size, and belt-usage status, offers possible enhancements in occupant protection. Designing a restraint system boils down to the determination of the design variables of either the restraint technologies or vehicle interiors. A restraint system of adaptive technologies involves much more design variables than a restraint system containing only load-limited belts and dual stage inflators, possibly posing a challenge to safety engineers. In this paper, a genetic algorithm (GA) tailored for restraint system optimization will be presented.