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Through the last decade ESA (European Space Agency) have developed a TGM (Trace Gas Monitoring) system for spacecraft air analysis from paper study to a fully operational breadboard [1–9]. The TGM system is a combination of FTIR spectrometry and specially developed analysis techniques. Ongoing work aims at a system flight experiment on e.g. the Space Shuttle early in 2003 [10]. This paper mainly covers the application of the TGM breadboard for a competitive blind testing on unknown multi-gas mixtures arranged by NASA. The TGM HW was applied as is, but a special calibration for the NASA test scenario was made. Four different system suppliers competed in the testing, and the ESA TGM system performed clearly best [11]. This independently defined and supervised testing has confirmed that the ESA TGM system is reliable to perform quasi-real time gas measurements in the concentration ranges required by ESA.