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The implementation of Advanced Life Support Systems (ALSS) for missions of long duration is inevitable. Many research works have been conducted on systems which would eventually become part of an ALSS. However, when the actual integration takes place, compatibility of different systems may become another issue and require further research, redesign, and modifications to the hardware, controls and its programs. An uncoordinated design process will result in a costly integration effort later. If a main system with all possible integrations were adopted now, it would greatly reduce development costs and time. In the design of the subsystems, known parameters provided by researchers should be regarded. These subsystems can produce fermented foods, mushrooms, bean sprouts, escargot, radish and vinegar. Ecologically balanced subsystems include heat and water recirculation systems and biofilters with microbes and other biomedical material.