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An age-dependent, serious-to-fatal (AIS3+), thoracic risk curve was derived and evaluated for frontal impacts. The study consisted of four parts. In Part 1, two datasets of post mortem human subjects (PMHS) were generated for statistical and sensitivity analyses. In Part 2, logistic regression analyses were conducted. For each dataset, two statistical methods were applied: (1) a conventional maximum likelihood method, and (2) a modified maximum likelihood method. Therefore, four statistical models were derived — one for each dataset/statistical method combination. For all of the resulting statistical models (risk curves), the linear combination of maximum normalized sternum deflection and age of the PMHS was identified as a feasible predictor of AIS3+ thoracic injury probability. In Part 3, the PMHS-based risk curves were transformed into test-dummy-based risk curves. In Part 4, validation studies were conducted for each risk curve.