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The Columbus Attached Pressurized Module (APM), part of the International Space Station (ISS), will support scientific, technological and commercial activities in a low earth orbit micro-gravity environment. Basic and applied research, technology development and demonstration will be accomplished in areas such as material sciences, life sciences and fluid physics. The APM, now in the detailed design C/D phase, will provide location for ten International Standard Payload Racks (ISPRs) and three storage racks, in an atmospheric pressure “shirt-sleeve” environment. The maintaining of habitable conditions and the provision of essential thermal-environmental services to payloads will be ensured by the APM Environmental Control System (ECS), as defined on the Columbus Payload Accommodation Handbook, Appendix C. The ECS will control cabin air pressure, composition, temperature and humidity and module surface temperatures, to ensure suitable environmental conditions for crew and ISPRs.