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The Internal Thermal Control System (ITCS) has been developed jointly by Boeing Corporation, Huntsville, Alabama and Honeywell Engines & Systems, Torrance, California to meet the internal thermal control needs for the International Space Station (ISS). The ITCS provides heat removal for the critical life support systems and thermal conditioning for numerous experiment racks. The ITCS will be fitted on a number of modules on the ISS. The first US Element containing the ITCS, Node 1, was launched in December 1998. Since Node 1 does not contain a pump to circulate the fluid it was not filled with ITCS fluid until after the US Laboratory Module was installed. The second US Element module, US Laboratory Module, which contains the pumps and all the major ITCS control hardware, was launched in February 2001. The third US Element containing the ITCS, the US Airlock, was launched in July 2001.

The advanced inflatable airlock (AIA) system was developed for the Space Launch Initiative (SLI). The objective of the AIA system is to greatly reduce the cost associated with performing extravehicular activity (EVA) from manned launch vehicles by reducing launch weight and volume from previous hard airlock systems such as the Space Shuttle and Space Station airlocks. The AIA system builds upon previous technology from the TransHab inflatable structures project, from Space Shuttle and Space Station Airlock systems, and from terrestrial flexible structures projects. The AIA system design is required to be versatile and capable of modification to fit any platform or vehicle needing EVA capability. During the basic phase of the program, the AIA conceptual design and key features were developed to help meet the SLI program goals of reduced cost and program risk.

The International Space Station (ISS) internal thermal control system (ITCS) has been developed jointly by the Boeing Corporation, Huntsville, Alabama, and Honeywell Engines & Systems, Torrance, California, to meet ISS internal thermal control needs. The ITCS provides heat removal for the critical life support systems and thermal conditioning for numerous experiment racks. The ITCS will be fitted on a number of modules on the ISS. The first module, the US Laboratory Module, was launched in February 2001 and is now operational on the ISS. The dual loop system is comprised of a low-temperature loop (LTL) and a moderate-temperature loop (MTL). Each loop has a pump package assembly (PPA), a system flow control assembly (SFCA), a three-way mixing valve (TWMV), several rack flow control assemblies (RFCA), cold plates, pressure sensors, temperature sensors, a pump bypass assembly (PBA), and a heat exchanger.