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During the twelve month period comprising Expeditions 10 and 11, the chemical quality of the potable water onboard the International Space Station (ISS) was verified through the return and ground analysis of water samples. The two-man Expedition 10 crew relied solely on Russian-provided ground water and reclaimed cabin humidity condensate as their sources of potable water. Collection of archival water samples with U.S. hardware has remained extremely restricted since the Columbia tragedy because of very limited return volume on Russian Soyuz vehicles. As a result only two such samples were collected during Expedition 10 and returned on Soyuz 9. The average return sample volume was only 250 milliliters, which limited the breadth of chemical analysis that could be performed. Despite the Space Shuttle vehicle returning to flight in July 2005, only two potable water samples were collected with U.S. hardware during Expedition 11 and returned on Shuttle flight STS-114 (LF1).