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One of the proposed methods for monitoring the microbial quality of the water supply aboard the International Space Station is membrane filtration. We adapted this method for space flight by using an off-the-shelf filter unit developed by Millipore. This sealed unit allows liquid to be filtered through a 0.45 μm cellulose acetate filter that sits atop an absorbent pad to which growth medium is added. We combined a tetrazolium dye with R2A medium to allow microbial colonies to be seen easily, and modified the medium to remain stable over 70 weeks at 25°C. This hardware was assembled and tested in the laboratory and during parabolic flight; a modified version was then flown on STS-66. After the STS-66 mission, a back-up plastic syringe and an all-metal syringe pump were added to the kit, and the hardware was used successfully to evaluate water quality aboard the Russian Mir space station.

As a more permanent human presence in space is established during future missions, crew health issues will require additional attention. Since a physician will not be a part of most crews, the flight surgeons will require more clinical information than can currently be provided to regularly assess crew health status and direct medical treatment. The Telemedicine Instrumentation Pack (TIP) is being designed to enable the Crew Medical Officers (CMO) in space to acquire the necessary medical information for telemedical consultation with the flight surgeons in the Mission Control Center (MCC). To date, two prototypes of the TIP have been developed, with the first being clinically evaluated in a local telemedicine testbed in the Fall of 1994 and the second prototype being recently completed. The current system concept, progress in the development of the system, plans for future development, and the evolution of the system are described.

NASA flight surgeons have routinely relied on telemedicine to augment inflight medical care since the Gemini program. The current telemedicine capability aboard the Space Shuttle is limited to two-way voice communication, one-way video, and telemetry of ECG and spacecraft parameters. This capability has been sufficient to manage the routine minor medical problems that have occurred in-flight, but long-duration Space Shuttle and International Space Station missions are likely to be accompanied by more serious medical contingencies. In the event of emergent crew health problems, NASA flight surgeons will require an improved capability to provide a rapid, accurate assessment of an ill or injured crewmember. Onboard systems will supply flight surgeons and medical specialty consultants with real-time voice communication, medical video, and data.

The objective of this study was to investigate combining GC/MS and CE methods to allow sub-mg/L levels of organic acids to be determined in various water samples. This study also served as a basis for evaluating these instruments for in-flight spacecraft water-quality monitoring and to help determine the modifications needed to convert terrestrial hardware for use in microgravity environments. This paper reports on current GC/MS and CE method development and data generated from some recent spacecraft-related water samples. Plans for further method development are also discussed.

Since the early years of the manned space program, NASA has developed and used exposure limits called Spacecraft Maximum Allowable Concentrations (SMACs) to help protect astronauts from airborne toxicants. Most of these SMACS are based on an exposure duration of 7 days, since this is the duration of a “typical” mission. A set of “contingency SMACs” is also being developed for scenarios involving brief (1-hour or 24- hour) exposures to relatively high levels of airborne toxicants from event-related “contingency” releases of contaminants. The emergency nature of contingency exposures dictates the use of different criteria for setting exposure limits. The NASA JSC Toxicology Group recently began a program to document the rationales used to set new SMACs and plans to review the older, 7-day SMACs. In cooperation with the National Research Council's Committee on Toxicology, a standard procedure has been developed for researching, setting, and documenting SMAC values.

With the restructure and funding changes for Space Station Freedom, the Environmental Health System (EHS)/Microbiology Subsystem revised its scheduling and operational requirements for component hardware. The function of the Microbiology Subsystem is to monitor the environmental quality of air, water, and internal surfaces and, in part, crew health on board Space Station. Its critical role shall be the identification of microbial contaminants in the environment that may cause system degradation, produce unsanitary or pathogenic conditions, or reduce crew and mission effectiveness. EHS/Microbiology operations and equipment shall be introduced in concert with a phased assembly sequence, from Man Tended Capability (MTC) through Permanently Manned Capability (PMC). Effective Microbiology operations and subsystem components will assure a safe, habitable, and useful spacecraft environment for life sciences research and long-term manned exploration.

Health of space explorers is a requisite for success of human exploration missions and, potentially, for return of explorers to Earth. Continuous, long term existence and complex, potentially hazardous tasks in space environments will challenge health of explorers. Immediate return to Earth will not be possible. Health care systems are being designed to address these concerns, starting from the requirement to maintain health of crew members throughout all mission phases, and the assumption that clinical (medical), preventive, and occupational health care will be necessary in space as on Earth. Systems for medical care, health monitoring and countermeasures, and environmental monitoring and countermeasures are being designed. Basic system definition concepts include an individual crew member, a crew surgeon, remote consultation, equipment, and work area or volume within space habitats that is dedicated for health care.