Search Results

An anatomically detailed rhesus monkey brain FE model was developed to simulate in vivo responses of the brain of sub-human primates subjected to rotational accelerations resulting in diffuse axonal injury (DAI). The material properties used in the monkey model are those in the GHBMC 50th percentile male head model (Global Human Body Model Consortium). The angular loading simulations consisted of coronal, oblique and sagittal plane rotations with the center of rotation in neck to duplicate experimental conditions. Maximum principal strain (MPS) and Cumulative strain damage measure (CSDM) were analyzed for various white matter structures such as the cerebrum subcortical white matter, corpus callosum and brainstem.

There has been recent progress over the past 10 years in research comparing 6-year-old thoracic and abdominal response of pediatric volunteers, pediatric post mortem human subjects (PMHS), animal surrogates, and 6-year-old ATDs. Although progress has been made to guide scaling laws of adult to pediatric thorax and abdomen data for use in ATD design and development of finite element models, further effort is needed, particularly with respect to lateral impacts. The objective of the current study was to use the impact response data of age equivalent swine from Yaek et al. (2018) to assess the validity of scaling laws used to develop lateral impact response corridors from adult porcine surrogate equivalents (PSE) to the 3-year-old, 6-year-old, and 10-year-old for the thorax and abdominal body regions.

Analysis and validation of current scaling relationships and existing response corridors using animal surrogate test data is valuable, and may lead to the development of new or improved scaling relationships. For this reason, lateral pendulum impact testing of appropriate size cadaveric porcine surrogates of human 3-year-old, 6-year-old, 10-year-old, and 50th percentile male age equivalence, were performed at the thorax and abdomen body regions to compare swine test data to already established human lateral impact response corridors scaled from the 50th percentile human adult male to the pediatric level to establish viability of current scaling laws. Appropriate Porcine Surrogate Equivalents PSE for the human 3-year-old, 6-year-old, 10-year-old, and 50th percentile male, based on whole body mass, were established. A series of lateral impact thorax and abdomen pendulum testing was performed based on previously established scaled lateral impact assessment test protocols.

An understanding of stiffness characteristics of different body regions, such as thorax, abdomen and pelvis of ES-2re and SID-IIs dummies under controlled laboratory test conditions is essential for development of both compatible performance targets for countermeasures and occupant protection strategies to meet the recently updated FMVSS214, LINCAP and IIHS Dynamic Side Impact Test requirements. The primary purpose of this study is to determine the transfer functions between the ES-2re and SID-IIs dummies for different body regions under identical test conditions using flat rigid wall sled tests. The experimental set-up consists of a flat rigid wall with five instrumented load-wall plates aligned with dummy’s shoulder, thorax, abdomen, pelvis and femur/knee impacting a stationary dummy seated on a rigid low friction seat at a pre-determined velocity.

The main purpose of this study was to determine the impact responses of the different body regions (shoulder, thorax, abdomen and pelvis/leg) of the ES-2re and SID-IIs dummies using rigid wall impacts under different initial test conditions. The experimental set-up consisted of a flat rigid wall with five instrumented load-wall plates aligned with dummy’s shoulder, thorax, abdomen, pelvis and knee impacting a stationary dummy seated on a rigid seat at a pre-determined velocity. The relative location and orientation of the load-wall plates was adjusted relative to the body regions of the ES-2re and SID-IIs dummies respectively.

The main purpose of this study was to determine the impact responses of the different body regions (shoulder, thorax, abdomen and pelvis/leg) of the ES-2re and SID-IIs dummies using rigid wall impacts under different initial test conditions. The experimental set-up consisted of a flat rigid wall with five instrumented load-wall plates aligned with dummy’s shoulder, thorax, abdomen, pelvis and knee impacting a stationary dummy seated on a rigid seat at a pre-determined velocity. The relative location and orientation of the load-wall plates was adjusted relative to the body regions of the ES-2re and SID-IIs dummies respectively.

A modified Marmarou impact acceleration injury model was developed to study the kinematics of the rat head to quantify traumatic axonal injury (TAI) in the corpus callosum (CC) and brainstem pyramidal tract (Py), to determine injury predictors and to establish injury thresholds for severe TAI. Thirty-one anesthetized male Sprague-Dawley rats (392 ± 13 grams) were impacted using a modified impact acceleration injury device from 2.25 m and 1.25 m heights. Beta-amyloid precursor protein (β-APP) immunocytochemistry was used to assess and quantify axonal changes in CC and Py. Over 600 injury maps in CC and Py were constructed in the 31 impacted rats. TAI distribution along the rostro-caudal direction in CC and Py was determined. Linear and angular responses of the rat head were monitored and measured in vivo with an attached accelerometer and angular rate sensor, and were correlated to TAI data.

EuroNCAP and regulations in Europe and Japan evaluate the pedestrian protection performance of cars. The test methods are similar and they all have requirements for the passive protection of the hood area at a pedestrian to car impact speed of 40 km/h. In Europe, a proposal for a second phase of the regulation mandates a brake-assist system along with passive requirements. The system assists the driver in optimizing the braking performance during panic braking, resulting in activation only when the driver brakes sufficiently. In a European study this was estimated to occur in about 50% of pedestrian accidents. A future system for brake assistance will likely include automatic braking, in response to a pre-crash sensor, to avoid or mitigate injuries of vulnerable road users. An important question is whether these systems will provide sufficient protection, or if a parallel, passive pedestrian protection system will be necessary.

The pia-arachnoid complex (PAC) covering the brain plays an important role in the mechanical response of the brain due to impact or inertial loading. However, the mechanical properties of the pia-arachnoid complex and its influence on the overall response of the brain have not been well characterized. Consequently, finite element (FE) brain models have tended to oversimplify the response of the pia-arachnoid complex, possibly resulting in a loss of accuracy in the model predictions. The aim of this study was to determine, experimentally, the material properties of the pia-arachnoid complex under quasi-static and dynamic loading conditions. Specimens of the pia-arachnoid complex were obtained from the parietal and temporal regions of freshly slaughtered bovine subjects with the specimen orientation recorded. Single-stroke, uniaxial quasi-static and dynamic tensile experiments were performed at strain-rates of 0.05, 0.5, 5 and 100 s-1 (n = 10 for each strain rate group).

Traumatic brain injury (TBI) continues to be a major health problem, with over 500,000 cases per year with a societal cost of approximately $85 billion in the US. Motor vehicle accidents are the leading cause of such injuries. In many cases of TBI widespread disruption of the axons occurs through a process known as diffuse axonal injury (DAI) or traumatic axonal injury (TAI). In the current study, an in vivo TAI model was developed using spinal nerve roots of adult rats. This model was used to determine functional and structural responses of axons to various strains and displacement rates. Fifty-six L5 dorsal nerve roots were each subjected to a predetermined strain range (<10%, 10-20% and >20%) at a specified displacement rate (0.01 mm/sec and 15 mm/sec) only once. Image analysis was used to determine actual strains on the roots during the pull.

Complete validation of any finite element (FE) model of the human brain is very difficult due to the lack of adequate experimental data. However, more animal brain injury data, especially rat data, obtained under well-defined mechanical loading conditions, are available to advance the understanding of the mechanisms of traumatic brain injury. Unfortunately, internal response of the brain in these experimental studies could not be measured. The aim of this study was to develop a detailed FE model of the rat brain for the prediction of intracranial responses due to different impact scenarios. Model results were used to elucidate possible brain injury mechanisms. An FE model, consisting of more than 250,000 hexahedral elements with a typical element size of 100 to 300 microns, was developed to represent the brain of a rat. The model was first validated locally against peak brain deformation data obtained from nine unique dynamic cortical deformation (vacuum) tests.

In the automotive seating industry measurements of lumbar support prominence and height are performed to assess their effects on occupant comfort. This project investigated measurement methods for lumbar support prominence and height in an occupied seat. Fifteen participants provided subjective responses of their perceived lumbar support prominence and height utilizing specifically developed visual analog scales. Also, pressure measurements were taken while the participants were seated. The recently developed H-point manikin II was utilized as a standardized sitter. Specifically, the lumbar support prominence (LSP) measure was used for the prominence measures. Pressure mat readings with the seated manikin was used for lumbar support height determination and prominence correlations. With both manikin and participants in the seat, the lumbar support was digitized through the rear of the seat.

Previous studies have shown that both excessive linear and rotational accelerations are the cause of head injuries. Although the head injury criterion has been beneficial as an indicator of head injury risk, it only considers linear acceleration, so there is a need to consider both types of motion in future safety standards. Advanced models of the head/brain complex have recently been developed to gain a better understanding of head injury biomechanics. While these models have been verified against laboratory experimental data, there is a lack of suitable real-world data available for validation. Hence, using two computer models of the head/brain, the objective of the current study was to reconstruct four real-world crashes with known head injury outcomes in a full-vehicle crash laboratory, simulate head/brain responses using kinematics obtained during these reconstructions, and to compare the results predicted by the models against the actual injuries sustained by the occupant.

Cervical facet joints are implicated as a major source of pain after whiplash injury. The purpose of this study was to investigate the proposed capsule strain injury mechanism of whiplash pain using neurophysiologic methods. Strain thresholds, threshold distribution, saturation strains and afterdischarge responses of capsule neural receptors were characterized in vivo. Goat C5-C6 facet joint capsules were used to identify and characterize capsule receptors in response to controlled uniaxial stretch by recording C6 dorsal rootlet nerve discharge. The joints were stretched at 0.5 mm/sec in a series of tests with 2 mm increments until the capsule ruptured. Ninety-two identified units were responsive to physiologic or noxious stretch while 28 were silent receptors. Among the 50 characterized responsive units, 42 showed low strain thresholds at 10.2±4.6% while 8 had high strain thresholds at 47.2±9.6%.

To date, several lateral impact studies (Bolte et al., 2000, 2003, Marth, 2002 and Compigne et al., 2004) have been performed on the shoulder to determine the response characteristics and injury threshold of the shoulder complex. Our understanding of the biomechanical response and injury tolerance of the shoulder would be improved if the results of these tests were combined. From a larger data base shoulder injury tolerance criteria can be developed as well as corridors for side impact dummies. Data from the study by Marth (2002, 12 tests) was combined with data from the previous studies. Twenty-two low speed tests (4.5 ± 0.7 m/s) and 9 high speed tests (6.7 ± 0.7 m/s) were selected from the combined data for developing corridors. Shoulder force, deflection and T1y acceleration corridors were developed using a minimization of cumulative variance technique.

Traumatic rupture of the aorta (TRA) is a leading cause of death in high velocity blunt trauma, particularly motor vehicle accidents. However, little is understood about the mechanisms of TRA and thus, the opportunities to prevent TRA in the motor vehicle environment are compromised. The objective of this study was to determine the relationship between impact response and TRA through analyses of data from cadaver tests that successfully produced TRA in lateral impacts. Seventeen Heidelberg-style side impact sled tests were conducted using unembalmed human cadavers. Three sled speeds were used: 6.7, 9.0, and 10.5 m/s. Three barrier configurations were used: rigid flat wall, rigid wall with a 152-mm offset toward the pelvis, and a flat wall with padding of varying stiffness. Multiple load and acceleration measurements were made on the barrier and cadaver. Potential injury parameters were evaluated and their relative predictive abilities were examined.

The objective of this work was to evaluate a new tool for assessing brain injury. Many race car drivers have suffered concussion and other brain injuries and are in need of ways of evaluating better head protective systems and equipment. Current assessment guidelines such as HIC may not be adequate for assessing all scenarios. Finite element models of the brain have the potential to provide much better injury prediction for any scenario. At a previous Motorsports conference, results of a MADYMO model of a racing car and driver driven by 3-D accelerations recorded in actual crashes were presented. Model results from nine cases, some with concussion and some not, yielded head accelerations that were used to drive the Wayne State University Head Injury Model (WSUHIM). This model consists of over 310,000 elements and is capable of simulating direct and indirect impacts. It has been extensively validated using published cadaveric test data.

Brain tissue architecture consists of a complex network of neurons and vasculature interspersed within a matrix of supporting cells. The role of the relatively suffer blood vessels on the more compliant brain tissues during rapid loading has not been properly investigated. Two 2-D finite element models of the human head were developed. The basic model (Model I) consisted of the skull, dura matter, cerebral spinal fluid (CSF), tentorium, brain tissue and the parasagittal bridging veins. The pia mater was also included but in a simplified form which does not correspond to the convolutions of the brain. In Model II, major branches of the cerebral arteries were added to Model I. Material properties for the brain tissues and vasculature were taken from those reported in the literature. The model was first validated against intracranial pressure and brain/skull relative motion data from cadaveric tests.

The biomechanical response and injury tolerance of the shoulder in lateral impacts is not well understood. These data are needed to better understand human injury tolerance, validate finite element models and develop biofidelic shoulders in side impact dummies. Seventeen side impact sled tests were performed with unembalmed human cadavers. Data analyzed for this study include T1-Y acceleration, shoulder and thoracic load plate forces, upper sternum x and y accelerations, and struck side acromion x, y and z accelerations. One dimensional deflection at the shoulder level was determined from high-speed film by measuring the distance between a target on T1 and the impacted wall. Force-time response corridors were obtained for tests with 9 m/s pelvic offset, 10.5 m/s pelvic offset, 9 m/s unpadded flat wall, 6.7 m/s unpadded flat wall, 9 m/s soft padding and 9 m/s stiff padding. Maximum shoulder plate forces in unpadded 9 m/s tests (5.5 kN) were larger than in 6.7 m/s tests (3.3 kN).

The purpose of this study is to help understand the thoracic response and injury mechanisms in high-energy, limited-stroke, lateral velocity pulse impacts to the human chest wall. To impart such impacts, a linear impactor was developed which had a limited stroke and minimally decreased velocity during impact. The peak impact velocity was 5.6 ± 0.3 m/s. A series of BioSID and cadaver tests were conducted to measure biomechanical response and injury data. The conflicting effects of padding on increased deflection and decreased acceleration were demonstrated in tests with BioSID and cadavers. The results of tests conducted on six cadavers were used to test several proposed injury criteria for side impact. Linear regression was used to correlate each injury criterion to the number of rib fractures. This test methodology captured and supported a contrasting trend of increased chest deflection and decreased TTI when padding was introduced.