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The analysis presented in this paper focuses on the metabolic consumption of oxygen by the crew onboard the International Space Station (ISS) during Expedition 12. The Russian Elektron, which electrolyzes water to produce oxygen, operational and non-operational periods are used to assist in the calculation of metabolic oxygen consumption. Non-operational periods will be used to establish baseline crew consumption rates. The importance of this analysis is to provide more accurate trend of oxygen metabolic consumption rates for Expedition 12.