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Determining the fundamental role of gravity in vital biological systems in space is one of six science and research areas that provides the philosophical underpinning for why NASA exists. The study of cells, tissues, and microorganisms in a spaceflight environment holds the promise of answering multiple intriguing questions about how gravity affects living systems. To enable these studies, specimens must be maintained in an environment similar to that used in a laboratory. Cell culture studies under normal laboratory conditions involve maintaining a highly specialized environment with the necessary temperature, humidity control, nutrient, and gas exchange conditions. These same cell life support conditions must be provided by the International Space Station (ISS) Cell Culture Unit (CCU) in the unique environment of space. The CCU is a perfusion-based system that must function in microgravity, at unit gravity (1g) on earth, and from 0.1g up to 2g aboard the ISS centrifuge rotor.

The National Space Biomedical Research Institute (NSBRI), established in 1997, is a twelve-university consortium dedicated to research that will impact mankind's next exploratory steps. The NSBRI's Education and Public Outreach Program (EPOP), is supporting NASA's education mission to, “Inspire the next generations…as only NASA can,” through a comprehensive Kindergarten through post-doctoral education program. The goals of the EPOP are to: communicate space exploration biology to schools; support undergraduate and graduate space-based courses and degrees; fund postdoctoral fellows to pursue space life sciences research; and engage national and international audiences to promote understanding of how space exploration benefits people on Earth. NSBRI EPOP presents its accomplishments as an educational strategy for supporting science education reform, workforce development, and public outreach.