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A 3-D finite element human head model has been developed to study the dynamic response of the human head to direct impact by a rigid impactor. The model simulated closely the main anatomical features of an average adult head. It included the scalp, a three-layered skull, cerebral spinal fluid (CSF), dura mater, falx cerebri, and brain. The layered skull, cerebral spinal fluid, and brain were modeled as brick elements with one-point integration. The scalp, dura mater, and falx cerebri were treated as membrane elements. To simulate the strain rate dependent characteristics of the soft tissues, the brain and the scalp were considered as viscoelastic materials. The other tissues of the head were assumed to be elastic. The model contains 6080 nodes, 5456 brick elements, and 1895 shell elements. To validate the head model, it was impacted frontally by a cylinder to simulate the cadaveric tests performed by Nahum et. al. (8).

Two-dimensional finite element models for three coronal sections of the porcine brain have been developed and the results were compared with injury data from animal experiments performed at the University of Pennsylvania (Ross et al, 1994). The models consisted of a three-layered skull, dura, CSF, white matter, gray matter and ventricles. Model I, a section at the septal nuclei and anterior commissure level, contains 490 solid elements and 108 membrane elements. Model II, a section at the rostral-thalamic level, contains 644 solid elements and 130 membrane elements. Model III, a section at the caudal hippocampal level, contains 548 solid elements and 104 membrane elements. Plane strain conditions were assumed for all models. Material properties of the brain were taken from previous human brain models, but the white matter was assumed to be about 60% stronger than the gray matter with the same Poisson's ratio.

A new three-dimensional human head finite element model, consisting of the scalp, skull, dura, falx, tentorium, pia, CSF, venous sinuses, ventricles, cerebrum (gray and white matter), cerebellum, brain stem and parasagittal bridging veins has been developed and partially validated against experimental data of Nahum et al (1977). A frontal impact and a sagittal plane rotational impact were simulated and impact responses from a homogeneous brain were compared with those of an inhomogeneous brain. Previous two-dimensional simulation results showed that differentiation between the gray and white matter and the inclusion of the ventricles are necessary in brain modeling to match regions of high shear stress to locations of diffuse axonal injury (DAI). The three-dimensional simulation results presented here also showed the necessity of including these anatomical features in brain modeling.

The mechanisms of knee fracture were studied experimentally using cadaveric knees and analytically by computer simulation. Ten 90 degree flexed knees were impacted frontally by a 20 kg pendulum with a rigid surface, a 450 psi (3.103 MPa) crush strength and a 100 psi (0.689 MPa) crush strength aluminum honeycomb padding and a 50 psi (0.345 MPa) crush strength paper honeycomb padding at a velocity of about five m/s. During rigid surface impact, a patella fracture and a split condylar fracture were observed. The split condylar fracture was generated by the patella pushing the condyles apart, based on a finite element model using the maximum principal stress as the injury criterion. In the case of the 450 psi aluminum honeycomb padding, the split condylar fracture still occurred, but no patella fractures were observed because the honeycomb provided a more uniform distribution of patella load. No bony fractures in the knee area occurred for impacts with a 50 psi paper honeycomb padding.

Finite element models of human body segments have been developed in recent years. Numerical simulation could be helpful when understanding injury mechanisms and to make injury assessments. In the lower leg injury research in NISSAN, a finite element model of the human ankle/foot is under development. The mesh for the bony part was taken from the original model developed by Beaugonin et al., but was revised by adding soft tissue to reproduce realistic responses. Damping effect in a high speed contact was taken into account by modeling skin and fat in the sole of the foot. The plantar aponeurosis tendon was modeled by nonlinear bar elements connecting the phalanges to the calcaneus. The rigid body connection, which was defined at the toe in the original model for simplicity, was removed and the transverse ligaments were added instead in order to bind the metatarsals and the phalanges. These tendons and ligaments were expected to reproduce a realistic response in compression.

Seventeen Heidelberg type cadaveric side impact sled tests, two sled-to-sled tests, and forty-four pendulum tests have been conducted at Wayne State University, to determine human responses and tolerances in lateral collisions. This paper describes the development of a simplified finite element model of a human occupant in a side impact configuration to simulate those cadaveric experiments. The twelve ribs were modeled by shell elements. The visceral contents were modeled as an elastic solid accompanied by an array of discrete dampers. Bone condition factors were obtained after autopsy to provide material properties for the model. The major parameters used for comparison are contact forces at the level of shoulder, thorax, abdomen and pelvis, lateral accelerations of ribs 4 and 8 and of T12, thoracic compression and injury functions V*C, TTI and ASA.

Complete validation of any finite element (FE) model of the human brain is very difficult due to the lack of adequate experimental data. However, more animal brain injury data, especially rat data, obtained under well-defined mechanical loading conditions, are available to advance the understanding of the mechanisms of traumatic brain injury. Unfortunately, internal response of the brain in these experimental studies could not be measured. The aim of this study was to develop a detailed FE model of the rat brain for the prediction of intracranial responses due to different impact scenarios. Model results were used to elucidate possible brain injury mechanisms. An FE model, consisting of more than 250,000 hexahedral elements with a typical element size of 100 to 300 microns, was developed to represent the brain of a rat. The model was first validated locally against peak brain deformation data obtained from nine unique dynamic cortical deformation (vacuum) tests.

As early as the 1950's, Gurdjian and colleagues (Gurdjian et al., 1955) observed that brain injuries could occur by direct pressure loading without any global head accelerations. This pressure-induced injury mechanism was "forgotten" for some time and is being rekindled due to the many mild traumatic brain injuries attributed to blast overpressure. The aim of the current study was to develop a finite element (FE) model to predict the biomechanical response of rat brain under a shock tube environment. The rat head model, including more than 530,000 hexahedral elements with a typical element size of 100 to 300 microns was developed based on a previous rat brain model for simulating a blunt controlled cortical impact. An FE model, which represents gas flow in a 0.305-m diameter shock tube, was formulated to provide input (incident) blast overpressures to the rat model. It used an Eulerian approach and the predicted pressures were verified with experimental data.

Cerebral blood vessels are an integral part of the brain and may play a role in the response of the brain to impact. The purpose of this study was to quantify the effects of surrogate vessels on the deformation patterns of a physical model of the brain under various impact conditions. Silicone gel and tubing were used as surrogates for brain tissue and blood vessels, respectively. Two aluminum cylinders representing a coronal section of the brain were constructed. One cylinder was filled with silicone gel only, and the other was filled with silicone gel and silicone tubing arranged in the radial direction in the peripheral region. An array of markers was embedded in the gel in both cylinders to facilitate strain calculation via high-speed video analysis. Both cylinders were simultaneously subjected to a combination of linear and angular acceleration using a two-segment pendulum.