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The Advanced Life Support (ALS) Project has accelerated an effort to develop an On-line Project Information System (OPIS) for research and technology development (R&TD) data centralization and sharing. This paper presents the OPIS development strategy and status. OPIS is being built as an application framework consisting of an underlying Linux/Apache/MySQL/PHP (LAMP) stack and supporting class libraries, which provide database abstraction and automatic code generation. This approach simplifies the development and maintenance process. The approach also allows for quick adaptation to serve multiple Programs/Projects, although initial deployment is for an ALS module. Data will be located on a secure server at NASA Ames Research Center (ARC). Initial functionality of OPIS will involve a Web-based solicitation of project and technology data, directly from ALS Principal Investigators (PIs) through data collection forms.