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Due to the lack of biofidelity seen in GHBMC M50-O in rear-facing impact simulations involving interaction with the seat back in an OEM seat, it is important to explore how the boundary conditions might be affecting the biofidelity and potentially formulate methods to improve biofidelity of different occupant models in the future while also maintaining seat validity. This study investigated the influence of one such boundary condition, which is the seat back foam material properties, on the thorax and pelvis kinematics and injury outcomes of the GHBMC 50th M50-O model in a high-speed rear-facing frontal impact scenario, which involves severe occupant loading of the seat back. Two different seat back foam materials were used – a stiff foam with high densification and a soft foam with low densification. The peak magnitudes of the T-spine resultant accelerations of the GHBMC M50-O increased with the use of soft foam as compared to stiff foam.