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Computational Fluid Dynamics is a powerful instrument for PEM fuel cell systems development, testing and optimization. Considering the complication due to the multiple physical phenomena involved in the cell's operations, a good understanding of the micro-scale fluidic behavior in boundary layers is recommended: pressure drop along the reactants gas channels and the cooling channels has a sensible effect on parasite load in fuel cell systems (i.e. the power absorbed by the pump supplying the gases), as well as an important role in thermal transport. A correct thermal and fluid dynamic boundary layer prediction on the channel walls and the other contact surface with porous layers requires usually a dense finite element volumes discretization near wall, especially if laminar flows occur: therefore, the boundary layer computational cost tends to be the major one.