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In designing an automobile seat, it is important to minimize the fatigue experienced by the driver resulting from long-term sitting. In this study eight healthy male subjects participated in two group experiments that were A-group and B-group. Acupoints combined with magnetism stimuli were put on to the subjects for reducing postural fatigue in B-group during the simulated driving. The surface electromyography (sEMG) of muscle activity at L4/L5 as well as subjective self-reporting on fatigue were recorded and tested. Analyzing and comparing the EMG median frequency and the subjective evaluations between two groups a conclusion that acupoints combined with magnetism stimuli could reduce the driver postural fatigue was drawn.