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A set of devices for measurement of human balance orientation and eye movements in weightlessness was developed for neurovestibular experiments on Spacelab. The experiments involve astronaut motion, limb position changes, and moving visual fields, measurements are made of eye movements, muscular activity and orientation perception. This joint US/Canadian research program represent a group of closely related experiments designed to investigate space motion sickness, any associated changes in otolith-mediated responses occurring during weightlessness, and the continuation of changes to postflight conditions. The otoliths are a component of the vestibular apparatus which is located in the middle ear. It is responsible for maintaining the body's balance. Gravitational pull on the otoliths causes them to constantly appraise the nervous system of the position of the head with respect to the direction of gravity.

The fuel energy consumption of subsonic air transportation is examined. The focus is on identification and quantification of fundamental engineering design tradeoffs which drive the design of subsonic tube and wing transport aircraft. The sensitivities of energy efficiency to recent and forecast technology developments are also examined.

The aim of this study was to explore if fingernail delamination injury following EMU glove use may be caused by compression-induced blood flow occlusion in the finger. During compression tests, finger blood flow decreased more than 60%, however this occurred more rapidly for finger pad compression (4 N) than for fingertips (10 N). A pressure bulb compression test resulted in 50% and 45% decreased blood flow at 100 mmHg and 200 mmHg, respectively. These results indicate that the finger pad pressure required to articulate stiff gloves is more likely to contribute to injury than the fingertip pressure associated with tight fitting gloves.

Determining the fundamental role of gravity in vital biological systems in space is one of six science and research areas that provides the philosophical underpinning for why NASA exists. The study of cells, tissues, and microorganisms in a spaceflight environment holds the promise of answering multiple intriguing questions about how gravity affects living systems. To enable these studies, specimens must be maintained in an environment similar to that used in a laboratory. Cell culture studies under normal laboratory conditions involve maintaining a highly specialized environment with the necessary temperature, humidity control, nutrient, and gas exchange conditions. These same cell life support conditions must be provided by the International Space Station (ISS) Cell Culture Unit (CCU) in the unique environment of space. The CCU is a perfusion-based system that must function in microgravity, at unit gravity (1g) on earth, and from 0.1g up to 2g aboard the ISS centrifuge rotor.

The National Space Biomedical Research Institute (NSBRI), established in 1997, is a twelve-university consortium dedicated to research that will impact mankind's next exploratory steps. The NSBRI's Education and Public Outreach Program (EPOP), is supporting NASA's education mission to, “Inspire the next generations…as only NASA can,” through a comprehensive Kindergarten through post-doctoral education program. The goals of the EPOP are to: communicate space exploration biology to schools; support undergraduate and graduate space-based courses and degrees; fund postdoctoral fellows to pursue space life sciences research; and engage national and international audiences to promote understanding of how space exploration benefits people on Earth. NSBRI EPOP presents its accomplishments as an educational strategy for supporting science education reform, workforce development, and public outreach.

Human explorers of planetary surfaces would benefit greatly from a spacesuit design that facilitates locomotion. To aid in the development of such an extravehicular activity suit, a design effort incorporating the concept of mechanical counter pressure (MCP) was undertaken. Three-dimensional laser scanning of the human body was used to identify the main effects of knee flexion angle on the size and shape of the leg. This laser scanning quantified the changes in shape that must be supported by an MCP garment and the tension that must be developed to produce even MCP. Evaluation of a hybrid-MCP concept using inextensible materials demonstrated strong agreement between experimental data and a mathematical model with rigid cylinder geometry. Testing of a form-fitting garment on the right lower leg of a subject demonstrated successful pressure production. Further research is required to evaluate how evenly pressure can be distributed using the hybrid-MCP concept.

Extravehicular activity (EVA) is investigated through experiments testing an actual extravehicular mobility unit (EMU) performing several EVA tasks in the laboratory, and a dynamic model of the EMU space suit is developed. Building directly on earlier work in EVA simulation, the space suit model was created from mass, inertia, and performance data to augment the unsuited 12-segment human model used in previous studies. A modified Preisach model was used to mathematically describe the hysteretic torque characteristics of joints in a pressurized space suit, and implemented numerically based on observed suit parameters. Computational simulations, based loosely on a 1995 EVA involving manipulation of the Spartan astrophysics payload, were performed to observe the effect of suit constraints on simulated astronaut performance.