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A concept of LSS building for planetary stations is suggested on the basis of experience in the development, research and testing of physical/chemical regenerative LSS for long-duration ground-based bio-technical complexes of habitat support and for orbiting space stations. A gradual transition from integrated physical/chemical regenerative LSS to hybrid integrated physical/chemical and bio-technical LSS and finally to integrated bio-technical regenerative LSS, is suggested. It is shown that at all phases of integrated LSS development, the systems based on physical/chemical processes will be critical for correlating the interfaces between the biological components that process the products obtained in the bio-components, and enabling the vitality of integrated LSS under emergency situations. The interface of integrated LSS with base power supply system is outlined.