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After several decades of human spaceflight, the community of space-faring nations has accumulated a diverse and sometimes harrowing history of toxicological events that have plagued human space endeavors almost from the very beginning. Some lessons have been learned in ground-based test beds and others were discovered the hard way - when human lives were at stake in space. From such lessons one can build a risk-management framework for toxicological events to minimize the probability of a harmful exposure, while recognizing that we cannot predict all possible events. Space toxicologists have learned that relatively harmless compounds can be converted by air revitalization systems into compounds that cause serious harm to the crew.

Providing water necessary to maintain life support has been accomplished in spacecraft vehicles for over forty years. This paper will investigate how previous U.S. space vehicles provided potable water. The water source for the spacecraft, biocide used to preserve the water on-orbit, water stowage methodology, materials, pumping mechanisms, on-orbit water requirements, and water temperature requirements will be discussed. Where available, the hardware used to provide the water and the general function of that hardware will also be detailed. The Crew Exploration Vehicle (CEV or Orion) water systems will be generically discussed to provide a glimpse of how similar they are to water systems in previous vehicles. Conclusions, questions, and recommendations on strategies that could be applied to CEV based on previous spacecraft water system lessons learned will be made.

An evaporative heat sink has been designed and built by AlliedSignal for NASA's Johnson Space Center. The unit is a demonstrator of a primary heat exchanger for NASA's prototype Crew Return Vehicle (CRV), designated the X-38. The primary heat exchanger is responsible for rejecting the heat produced by both the flight crew and the avionics. Spacecraft evaporative heat sinks utilize space vacuum as a resource to control the vapor pressure of a liquid. For the X-38, water has been chosen as the heat transport fluid. A portion of this coolant flow is bled off for use as the evaporant. At sufficiently low pressures, the water can be made to boil at temperatures approaching its freezing point. Heat transferred to liquid water in this state will cause the liquid to evaporate, thus creating a heat sink for the spacecraft's coolant loop. The CRV mission requires the heat exchanger to be compact and low in mass.

The Spacesuit Water Membrane Evaporator (SWME) is the baseline heat rejection technology selected for development for the Constellation lunar suit. The first SWME prototype, designed, built, and tested at Johnson Space Center in 1999 used a Teflon hydrophobic porous membrane sheet shaped into an annulus to provide cooling to the coolant loop through water evaporation to the vacuum of space. This present study describes the test methodology and planning to compare the test performance of three commercially available hollow fiber materials as alternatives to the sheet membrane prototype for SWME, in particular, a porous hydrophobic polypropylene, and two variants that employ ion exchange through non-porous hydrophilic modified Nafion. Contamination tests will be performed to probe for sensitivities of the candidate SWME elements to ordinary constituents that are expected to be found in the potable water provided by the vehicle, the target feedwater source.

In a crewed spacecraft environment, atmospheric carbon dioxide (CO2) and moisture control are crucial. Hamilton Sundstrand has developed a stable and efficient amine-based CO2 and water vapor sorbent, SA9T, that is well suited for use in a spacecraft environment. The sorbent is efficiently packaged in pressure-swing regenerable beds that are thermally linked to improve removal efficiency and minimize vehicle thermal loads. Flows are controlled with a single spool valve. This technology has been baselined for the new Orion spacecraft, but additional data was needed on the operational characteristics of the package in a simulated spacecraft environment. One unit was tested with simulated metabolic loads in a closed chamber at Johnson Space Center during the latter part of 2006. Those test results were reported in a 2007 ICES paper.

The aim of this study was to explore if fingernail delamination injury following EMU glove use may be caused by compression-induced blood flow occlusion in the finger. During compression tests, finger blood flow decreased more than 60%, however this occurred more rapidly for finger pad compression (4 N) than for fingertips (10 N). A pressure bulb compression test resulted in 50% and 45% decreased blood flow at 100 mmHg and 200 mmHg, respectively. These results indicate that the finger pad pressure required to articulate stiff gloves is more likely to contribute to injury than the fingertip pressure associated with tight fitting gloves.

A generalized computer program for analysis of pressure and composition in multiple volume systems has been under development by the National Aeronautics and Space Administration (NASA) since 1976. This paper describes the most recent developments in the program. These improvements include the expansion of the program to nine volumes, improvements to the model of the International Space Station (ISS) carbon dioxide removal system, and addition of a detailed Sabatier carbon dioxide reduction mode. An evaluation of the feasibility of adding of trace contaminant tracking was also performed. This paper will also present the results of an analysis that compares model predictions with ISS flight data for carbon dioxide (CO2) maintenance.

During the period July 2001 to March 2002, the performance of a water-jacketed high intensity discharge lamp of advanced design was evaluated within a lamp test stand at The University of Arizona (UA), Controlled Environment Agriculture Center (CEAC) in Tucson, Arizona. The lamps and test stand system were developed by Mr. Phil Sadler of Sadler Machine Company, Tempe, Arizona, and supported by a Space Act Agreement between NASA-Johnson Space Center (JSC) and UA. The purpose was for long term testing of the prototype lamp and demonstration of an improved procedure for use of water-jacketed lamps for plant production within the close confines of controlled environment facilities envisioned by NASA within Bioregenerative Life Support Systems. The lamp test stand consisted of six, 400 watt water-cooled, high pressure sodium HID lamps, mounted within a framework.

The International Space Station (ISS) Active Thermal Control System (ATCS) (Ref. 1,2) has changed over the past several years to address problems and to improve its assembly and operation on-orbit. This paper captures the ways in which the Internal (I) ATCS and External (E) ATCS have changed design characteristics and operations both for the system currently operating on-orbit and the new elements of the system that are about to be added and/or activated. The rationale for changes in ATCS design, assembly and operation will provide insights into the lessons learned during ATCS development. The state of the assembly of the integrated ATCS will be presented to provide a status of the build-up of the system. The capabilities of the on-orbit system will be presented with a summary of the elements of the ISS ATCS that are functional on-orbit plus the plans for launch of remaining parts of the integrated ISS ATCS.

Biological water processors are currently being developed for application in microgravity environments. Work has been performed to develop a single-phase, gravity independent anoxic denitrification reactor for organic carbon removal [1]. As a follow on to this work it was necessary to develop a gravity independent nitrification reactor in order to provide sufficient nitrite and nitrate to the organic carbon oxidation reactor for the complete removal of organic carbon. One approach for providing the significant amounts of dissolved oxygen required for nitrification is to require the biological reactor design to process two-phase gas and liquid in micro-gravity. This paper addresses the design and test results overview for development of a tubular, two-phase, gravity independent nitrification biological water processor.

Since the early 1980’s, the Shuttle Extra Vehicular Activity (EVA) glove design has evolved to meet the challenge of space based tasks. These tasks have typically been satellite retrieval and repair or EVA based flight experiments. With the start of the International Space Station (ISS) assembly, the number of EVA based missions is increasing far beyond what has been required in the past; this has commonly been referred to as the “Wall of EVA’s”. To meet this challenge, it was determined that the evolution of the current glove design would not meet future mission objectives. Instead, a revolution in glove design was needed to create a high performance tool that would effectively increase crewmember mission efficiency. The results of this effort have led to the design, certification and implementation of the Phase VI EVA glove into the Shuttle flight program.

This paper provides an overview of the IMMWPS Integrated Ground Test Program, completed at the NASA Johnson Space Center (JSC) during October and November 2001. The JSC Crew and Thermal Systems Division (CTSD) has developed the IMMWPS orbital flight experiment to test the feasibility of a microbe-based water purifier for use in zero-gravity conditions. The IMMWPS design utilizes a Microbial Processor Assembly (MPA) inoculated with facultative anaerobes to convert organic contaminants in wastewater to carbon dioxide and biomass. The primary purpose of the ground test program was to verify functional operations and procedures. A secondary objective was to provide initial ground data for later comparison to on-orbit performance. This paper provides a description of the overall test program, including the test article hardware and the test sequence performed to simulate the anticipated space flight test program. In addition, a summary of significant results from the testing is provided.

The Major Constituent Analyzer (MCA) was activated on-orbit on 2/13/01 and provided essentially continuous readings of partial pressures for oxygen, nitrogen, carbon dioxide, methane, hydrogen and water in the ISS atmosphere. The MCA plays a crucial role in the operation of the Laboratory ECLSS and EVA operations from the airlock. This paper discusses the performance of the MCA as compared to specified accuracy requirements. The MCA has an on-board self-calibration capability and the frequency of this calibration could be relaxed with the level of instrument stability observed on-orbit. This paper also discusses anomalies the MCA experienced during the first year of on-orbit operation. Extensive Built In Test (BIT) and fault isolation capabilities proved to be invaluable in isolating the causes of anomalies. The process of fault isolation is discussed along with development of workaround solutions and implementation of permanent on-orbit corrections.

The International Space Station Waste Collector Subsystem Risk Mitigation Experiment (ISS WCS RME) was flown as the primary (Shuttle) WCS on Space Shuttle flight STS-104 (ISS-7A) in July 2001, to validate new design enhancements. In general, the WCS is utilized for collecting, storing, and compacting fecal & associated personal hygiene waste, in a zero gravity environment. In addition, the WCS collects and transfers urine to the Shuttle waste storage tank. All functions are executed while controlling odors and providing crew comfort. The ISS WCS previously flew on three Shuttle flights as the Extended Duration Orbiter (EDO) WCS, as it was originally designed to support extended duration Space Shuttle flights up to 30 days in length. Soon after its third flight, the Space Shuttle Program decided to no longer require 30 day extended mission duration capability and provided the EDO WCS to the ISS Program.

Gas-separation and reverse-osmosis membrane models are being developed in conjunction with membrane testing at NASA JSC. The completed gas-separation membrane model extracts effective component permeabilities from multicomponent test data, and predicts the effects of flow configuration, operating conditions, and membrane dimensions on module performance. Variable feed- and permeate-side pressures are considered. The model has been applied to test data for hollow-fiber membrane modules with simulated cabin-air feeds. Results are presented for a membrane designed for air drying applications. Extracted permeabilities are used to predict the effect of operating conditions on water enrichment in the permeate. A first-order reverse-osmosis model has been applied to test data for spiral wound membrane modules with a simulated hygiene water feed. The model estimates an effective local component rejection coefficient under pseudo-steady-state conditions.

Conceptual designs for a space suit Personal Life Support Subsystem (PLSS) were developed and assessed to determine if upgrading the system using new, emerging, or projected technologies to fulfill basic functions would result in mass, volume, or performance improvements. Technologies were identified to satisfy each of the functions of the PLSS in three environments (zero-g, Lunar, and Martian) and in three time frames (2006, 2010, and 2020). The viability of candidate technologies was evaluated using evaluation criteria such as safety, technology readiness, and reliability. System concepts (schematics) were developed for combinations of time frame and environment by assigning specific technologies to each of four key functions of the PLSS -- oxygen supply, waste removal, thermal control, and power. The PLSS concepts were evaluated using the ExtraVehicular Activity System Sizing Analysis Tool, software created by NASA to analyze integrated system mass, volume, power and thermal loads.

A small team of NASA engineers has been assembled at the Johnson Space Center, with the goal of developing an inexpensive space-capable vehicle. In order to minimize cost and development time of the experimental vehicle, it was desirable to build upon a previously-developed vehicle shape. The basic shape of the X-24A experimental lifting body was chosen for several reasons, and in the case of the Environmental Control and Life Support (ECLS), the de-orbit cross-range capability of this shape provides for a minimal on-orbit time while waiting for landing opportunities, which in turn simplifies the ECLS. Figure 1 shows the X-38 vehicle body shape. In keeping with the goal of rapidly developing an inexpensive and reliable vehicle, the ECLS was developed using simple, passive systems where practical. This paper provides an overview of the ECLS mission requirements and design, with emphasis on the philosophy used in its development.

Research committed by the Langley Research Center through 1995 resulting in the HZETRN code provides the current basis for shield design methods according to NASA STD-3000 (2005). With this new prominence, the database, basic numerical procedures, and algorithms are being re-examined with new methods of verification and validation being implemented to capture a well defined algorithm for engineering design processes to be used in this early development phase of the Bush initiative. This process provides the methodology to transform the 1995 HZETRN research code into the 2005 HZETRN engineering code to be available for these early design processes. In this paper, we will review the basic derivations including new corrections to the codes to insure improved numerical stability and provide benchmarks for code verification.

This ground-based study compared the risk of microbubbles during decompression under simulated space extravehicular activities (EVA) after three days of six-degree head-down bed rest with three days of ambulatory control. Test subjects were exposed to a pressure of 44.8 kPa (6.5 psi), breathed 100% oxygen, and exercised at reduced pressure either in the supine (during experimental) or upright (control) position. Circulating microbubbles were monitored by a precordial Doppler ultrasound device, and were found in 52% (12/23) of control and 26% (6/23) of experimental exposures. Survival analysis using Cox proportional hazards regression showed that there was 0.22 times (95% confidence interval=0.07-0.68) reduction in the risk of high grade microbubbles after bed rest, compared to controls (p=0.004). This finding is of importance in evaluating the risk of DCS during EVA.

Supply of oxygen (O2) and hydrogen (H2) by electrolyzing water in space will play an important role in meeting the National Aeronautics and Space Administration's (NASA's) needs and goals for future space missions. Both O2 and H2 are envisioned to be used in a variety of processes including crew life support, spacecraft propulsion, extravehicular activity, electrical power generation/storage as well as in scientific experiment and manufacturing processes. Life Systems, Inc., in conjunction with NASA, has been developing an alkaline-based Static Feed Electrolyzer (SFE). During the development of the water electrolysis technology over the past 23 years, an extensive engineering and scientific data base has been assembled.