Technical Paper
On the Importance of Nonlinearity of Brain Tissue Under Large Deformations
2003-10-27
2003-22-0005
Linear shear properties of human and bovine brain tissue were determined from transient stress-relaxation experiments and their material functions were compared. Quasi-linear viscoelastic theory was then utilized to determine material constants for bovine brain tissue subjected to large deformations. The range of applicability for linear and quasi-linear constitutive models of brain tissue was determined. A nonlinear Green-Rivlin constitutive model was subsequently applied to characterize temporal nonlinearity of bovine brain tissue in shear. Overall, 10 brain specimens from 5 fresh human cadavers and 156 brain specimens from 26 fresh bovine cadaver brains were used to quantify and compare shear brain responses under various loading conditions. The assumptions of homogeneity, isotropy, and incompressibility of brain material were made in order to reduce the required number of experiments.
