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This paper presents a new portable metabolic device (PUMA-Portable Unit for Metabolic Analysis) developed at the NASA Glenn Research Center. PUMA is a battery-operated, wearable unit to measure metabolic rate (minute ventilation, oxygen up-take, carbon dioxide output and heart rate) in a clinical setting, in the field or in remote, extreme environments. The critical sensors in PUMA are located close to the mouth and sampled at 10 Hz to allow intra-breath measurements. PUMA transmits metabolic data wirelessly to a remote computer for data analysis and storage. In addition to it's primary function as a portable metabolic measurement device, the PUMA sensors can also be easily adapted to other applications, including future EVA suits where they could measure metabolic rate for a suited crew member. The first section of the paper discusses the specific technologies and innovations of PUMA.